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    CG3604 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33593, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3604provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031562
    Locus tag
    Dmel_CG3604
    See related
    AllianceGenome:FB:FBgn0031562
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LP04037; Dmel\CG3604
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be active in extracellular space. Is expressed in embryonic large intestine. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3604 in Genome Data Viewer
    Location:
    24B3-24B3; 2-10 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3697242..3697872, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3697242..3697872, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Immune induced molecule 33 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila. Brun S, et al. Genes Cells, 2006 Apr. PMID 16611243
    2. Lactobacilli Modulate Epithelial Cytoprotection through the Nrf2 Pathway. Jones RM, et al. Cell Rep, 2015 Aug 25. PMID 26279578, Free PMC Article
    3. The Genomic Basis of Postponed Senescence in Drosophila melanogaster. Carnes MU, et al. PLoS One, 2015. PMID 26378456, Free PMC Article
    4. Temporally variable selection on proteolysis-related reproductive tract proteins in Drosophila. Wong A, et al. Mol Biol Evol, 2012 Jan. PMID 21940639, Free PMC Article
    5. Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Greene JC, et al. Hum Mol Genet, 2005 Mar 15. PMID 15689351

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3604-PA
    CG3604-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3697242..3697872 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298666.1 → NP_001285595.1  uncharacterized protein Dmel_CG3604, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285595.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQT9
      Conserved Domains (1) summary
      cd00109
      Location:53 → 106
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

    2. NM_134957.3 → NP_608801.1  uncharacterized protein Dmel_CG3604, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608801.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQT9
      Related
      FBpp0077234
      Conserved Domains (1) summary
      cd00109
      Location:53 → 106
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQT9 Q9VQT9

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