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    CG6527 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39197, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6527provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036085
    Locus tag
    Dmel_CG6527
    See related
    AllianceGenome:FB:FBgn0036085
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT13283; Dmel\CG6527
    Summary
    Predicted to enable protein-membrane adaptor activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6527 in Genome Data Viewer
    Location:
    67E4-67E4; 3-33 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (10557023..10559082, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (10550123..10552182, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene RNA-binding Fox protein 1 Neighboring gene Sperm-Leucylaminopeptidase 4 Neighboring gene ncRNA Neighboring gene long non-coding RNA:CR46212 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    2. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    3. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
    4. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
    5. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-membrane adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum-plasma membrane tethering IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6527-PA
    CG6527-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      10557023..10559082 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300092.1 → NP_001287021.1  uncharacterized protein Dmel_CG6527, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287021.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T474, Q9VT97
      Conserved Domains (1) summary
      pfam00635
      Location:8 → 110
      Motile_Sperm; MSP (Major sperm protein) domain

    2. NM_176315.2 → NP_788493.1  uncharacterized protein Dmel_CG6527, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788493.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T474, Q9VT97
      Related
      FBpp0076020
      Conserved Domains (1) summary
      pfam00635
      Location:8 → 110
      Motile_Sperm; MSP (Major sperm protein) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T474 Q8T474
    Q9VT97 Q9VT97

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