grau grauzone [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: grauprovided by FlyBase
Official Full Name: grauzoneprovided by FlyBase
Primary source: FLYBASE:FBgn0001133
Locus tag: Dmel_CG33133
See related: AllianceGenome:FB:FBgn0001133
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG3282; CG33133; Dmel\CG33133; Grau
Summary: Enables cis-regulatory region sequence-specific DNA binding activity. Involved in egg activation; female meiotic nuclear division; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including embryonic/larval midgut primordium; follicle cell; germarium; nurse cell; and ovary. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (21009764..21011921, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (16897269..16899426, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Efficient binding of ZADs from the proteins Grau, ZIPIC, and Zw5 to the translation elongation factor EF1alpha1 in nuclear and cytoplasmic extracts has been demonstrated.
Title: [Translation elongation factor EF1α1 interacts with ZAD domains of transcription factors from Drosophila melanogaster].
the zinc finger-associated domain of grauzone is a novel zinc-coordinating protein-protein interaction module
Title: The zinc finger-associated domain of the Drosophila transcription factor grauzone is a novel zinc-coordinating protein-protein interaction module.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cellularization	HMP more info	PubMed
involved_in egg activation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in female meiotic nuclear division	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in homologous chromosome segregation	TAS Traceable Author Statement more info	PubMed
involved_in pole cell formation	HMP more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain