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    Or1e16 olfactory receptor family 1 subfamily E member 16 [ Mus musculus (house mouse) ]

    Gene ID: 258923, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or1e16provided by MGI
    Official Full Name
    olfactory receptor family 1 subfamily E member 16provided by MGI
    Primary source
    MGI:MGI:102698
    See related
    Ensembl:ENSMUSG00000069823 AllianceGenome:MGI:102698
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    I54; Olfr1; MOR135-13
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or1e16 in Genome Data Viewer
    Location:
    11 B4; 11 45.33 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (73285902..73290321, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (73395076..73399495, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 1 subfamily E member 18 Neighboring gene lymphocyte antigen 6 complex, locus E pseudogene Neighboring gene olfactory receptor family 1 subfamily E member 36, pseudogene 1 Neighboring gene olfactory receptor family 1 subfamily E member 19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Odorant receptors govern the formation of a precise topographic map. Wang F, et al. Cell, 1998 Apr 3. PMID 9546391
    2. Allelic inactivation regulates olfactory receptor gene expression. Chess A, et al. Cell, 1994 Sep 9. PMID 8087849
    3. Sensitivity-dependent hierarchical receptor codes for odors. Hamana H, et al. Chem Senses, 2003 Feb. PMID 12588732
    4. Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding. Sato T, et al. Sci Rep, 2015 Sep 11. PMID 26361056, Free PMC Article
    5. Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Michaloski JS, et al. Genome Res, 2006 Sep. PMID 16902085, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 1E16
    Names
    GA_x6K02T2P1NL-3556334-3555390
    odorant receptor I54
    olfactory receptor 1
    olfactory receptor 135-13
    olfactory receptor MOR135-13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146921.2 → NP_667132.1  olfactory receptor 1E16

      See identical proteins and their annotated locations for NP_667132.1

      Status: VALIDATED

      Source sequence(s)
      AL645739, DR065653
      Consensus CDS
      CCDS25008.1
      UniProtKB/Swiss-Prot
      Q8VGI1
      Related
      ENSMUSP00000113707.2, ENSMUST00000120303.9
      Conserved Domains (2) summary
      pfam00001
      Location:41 → 290
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31 → 308
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      73285902..73290321 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246014.1 → XP_030101874.1  olfactory receptor 1E16 isoform X1

      Conserved Domains (1) summary
      cd15918
      Location:28 → 297
      7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VGI1.1 GenPept UniProtKB/Swiss-Prot:Q8VGI1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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