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    Tc00.1047053503613.40 pterin-4-alpha-carbinolamine dehydratase, putative [ Trypanosoma cruzi ]

    Gene ID: 3537394, updated on 23-Nov-2023

    Summary

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    Gene symbol
    Tc00.1047053503613.40
    Gene description
    pterin-4-alpha-carbinolamine dehydratase, putative
    Locus tag
    Tc00.1047053503613.40
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Trypanosoma cruzi (strain: CL Brener)
    Lineage
    Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum
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    Genomic context

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    See Tc00.1047053503613.40 in Genome Data Viewer
    Location:
    chromosome: Unknown
    Exon count:
    1

    NW_001849519.1Genomic Context describing neighboring genes Neighboring gene proteasome alpha 7 subunit, putative Neighboring gene DNA repair protein, putative Neighboring gene hypothetical protein Neighboring gene acidocalcisomal pyrophosphatase, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_001849519.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. El-Sayed NM, et al. Science, 2005 Jul 15. PMID 16020725
    2. Comparative genomics of trypanosomatid parasitic protozoa. El-Sayed NM, et al. Science, 2005 Jul 15. PMID 16020724
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    • heterozygous, Esmeraldo-like haplotype
      allele of Tc00.1047053511165.54

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4-alpha-hydroxytetrahydrobiopterin dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tetrahydrobiopterin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pterin-4-alpha-carbinolamine dehydratase, putative
    XP_807205.1
    • heterozygous, Esmeraldo-like haplotype
      allele of Tc00.1047053511165.54

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NW_001849519.1 Reference assembly

      Range
      102650..103123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_802112.1 → XP_807205.1  pterin-4-alpha-carbinolamine dehydratase, putative [Trypanosoma cruzi]

      See identical proteins and their annotated locations for XP_807205.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q4CYK3
      Conserved Domains (1) summary
      cd00914
      Location:71 → 149
      PCD_DCoH_subfamily_b; PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by ...
    Nucleotide Protein
    Heading Accession and Version

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