Isoc1 isochorismatase domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Isoc1provided by MGI
Official Full Name: isochorismatase domain containing 1provided by MGI
Primary source: MGI:MGI:1913557
See related: Ensembl:ENSMUSG00000024601 AllianceGenome:MGI:1913557
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2610034N03Rik
Summary: Predicted to be located in peroxisome. Predicted to be active in cytoplasm. Is expressed in brain. Orthologous to human ISOC1 (isochorismatase domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in subcutaneous fat pad adult (RPKM 28.1), genital fat pad adult (RPKM 26.3) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 18 D3; 18 33.71 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (58792554..58812642)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (58659482..58679570)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in peroxisome	ISO Inferred from Sequence Orthology more info
located_in peroxisome	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

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Preferred Names: isochorismatase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_025478.3 → NP_079754.2 isochorismatase domain-containing protein 1

See identical proteins and their annotated locations for NP_079754.2

Status: PROVISIONAL

Source sequence(s)

AC158924

Consensus CDS

CCDS29265.1

UniProtKB/Swiss-Prot

Q3U677, Q91V64

UniProtKB/TrEMBL

A0A494B952

Related

ENSMUSP00000025503.9, ENSMUST00000025503.10

Conserved Domains (1) summary

cd01012
Location:115 → 269

YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...