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    Sbno1 strawberry notch 1 [ Mus musculus (house mouse) ]

    Gene ID: 243272, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sbno1provided by MGI
    Official Full Name
    strawberry notch 1provided by MGI
    Primary source
    MGI:MGI:2384298
    See related
    Ensembl:ENSMUSG00000038095 AllianceGenome:MGI:2384298
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    sno; Sbno; mSno1; 9330180L10Rik
    Summary
    Predicted to enable chromatin DNA binding activity and histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and liver. Orthologous to human SBNO1 (strawberry notch homolog 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 13.5), testis adult (RPKM 12.3) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sbno1 in Genome Data Viewer
    Location:
    5 F; 5 63.54 cM
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (124506765..124564059, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (124368702..124426007, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene mitochondrial translation release factor in rescue Neighboring gene cyclin dependent kinase 2 associated protein 1 Neighboring gene STARR-seq mESC enhancer starr_14338 Neighboring gene STARR-positive B cell enhancer ABC_E851 Neighboring gene lysine methyltransferase 5A Neighboring gene Rab interacting lysosomal protein-like 2 Neighboring gene peptidylprolyl isomerase A pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC28589

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein strawberry notch homolog 1
    Names
    sno, strawberry notch homolog 1
    strawberry notch homolog 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081203.2NP_001074672.1  protein strawberry notch homolog 1 isoform a

      See identical proteins and their annotated locations for NP_001074672.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AC127339
      Consensus CDS
      CCDS39280.1
      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      UniProtKB/TrEMBL
      B2RRI2
      Related
      ENSMUSP00000066808.6, ENSMUST00000065263.12
      Conserved Domains (2) summary
      pfam13871
      Location:8701146
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:257559
      AAA_34; P-loop containing NTP hydrolase pore-1
    2. NM_001359978.1NP_001346907.1  protein strawberry notch homolog 1 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AC127339
      Consensus CDS
      CCDS39280.1
      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      UniProtKB/TrEMBL
      B2RRI2
      Related
      ENSMUSP00000142481.2, ENSMUST00000199808.5
      Conserved Domains (2) summary
      pfam13871
      Location:8701146
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:257559
      AAA_34; P-loop containing NTP hydrolase pore-1
    3. NM_001359979.1NP_001346908.1  protein strawberry notch homolog 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is 1 aa shorter compared to isoform a.
      Source sequence(s)
      AC127339
      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      UniProtKB/TrEMBL
      F7CVW0
      Conserved Domains (2) summary
      pfam13871
      Location:8691145
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:256558
      AAA_34; P-loop containing NTP hydrolase pore-1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      124506765..124564059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165129.1XP_036021022.1  protein strawberry notch homolog 1 isoform X2

      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      UniProtKB/TrEMBL
      F7CVW0
      Related
      ENSMUSP00000130860.3, ENSMUST00000168651.6
      Conserved Domains (2) summary
      pfam13871
      Location:8691145
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:256558
      AAA_34; P-loop containing NTP hydrolase pore-1
    2. XM_006530320.5XP_006530383.1  protein strawberry notch homolog 1 isoform X3

      See identical proteins and their annotated locations for XP_006530383.1

      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      Conserved Domains (2) summary
      pfam13871
      Location:8351111
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:222524
      AAA_34; P-loop containing NTP hydrolase pore-1
    3. XM_006530321.4XP_006530384.1  protein strawberry notch homolog 1 isoform X3

      See identical proteins and their annotated locations for XP_006530384.1

      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      Conserved Domains (2) summary
      pfam13871
      Location:8351111
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:222524
      AAA_34; P-loop containing NTP hydrolase pore-1
    4. XM_006530323.4XP_006530386.1  protein strawberry notch homolog 1 isoform X4

      See identical proteins and their annotated locations for XP_006530386.1

      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      Conserved Domains (2) summary
      pfam13871
      Location:8341110
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:221523
      AAA_34; P-loop containing NTP hydrolase pore-1
    5. XM_006530322.5XP_006530385.1  protein strawberry notch homolog 1 isoform X4

      See identical proteins and their annotated locations for XP_006530385.1

      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      Conserved Domains (2) summary
      pfam13871
      Location:8341110
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:221523
      AAA_34; P-loop containing NTP hydrolase pore-1
    6. XM_036165130.1XP_036021023.1  protein strawberry notch homolog 1 isoform X2

      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      UniProtKB/TrEMBL
      F7CVW0
      Conserved Domains (2) summary
      pfam13871
      Location:8691145
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:256558
      AAA_34; P-loop containing NTP hydrolase pore-1
    7. XM_006530318.4XP_006530381.1  protein strawberry notch homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_006530381.1

      UniProtKB/Swiss-Prot
      Q3KQK3, Q689Z5, Q8BVN5
      UniProtKB/TrEMBL
      B2RRI2
      Conserved Domains (2) summary
      pfam13871
      Location:8701146
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:257559
      AAA_34; P-loop containing NTP hydrolase pore-1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_145631.1: Suppressed sequence

      Description
      NM_145631.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.