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    HGF hepatocyte growth factor [ Colobus angolensis palliatus ]

    Gene ID: 105501675, updated on 13-Mar-2024

    Summary

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    Gene symbol
    HGF
    Gene description
    hepatocyte growth factor
    See related
    Ensembl:ENSCANG00000040348
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Colobus angolensis palliatus (sub-species: palliatus)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
    Orthologs
    human mouse all
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    Genomic context

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    See HGF in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012121154.1 (5355592..5424867)

    NW_012121154.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA desaturase pseudogene Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 1 Neighboring gene desmocollin-2 Neighboring gene semaphorin 3C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012121154.1 Unplaced Scaffold Reference Cang.pa_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hepatocyte growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hepatocyte growth factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cang.pa_1.0

    Genomic

    1. NW_012121154.1 Reference Cang.pa_1.0

      Range
      5355592..5424867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011927694.1 → XP_011783084.1  hepatocyte growth factor isoform X1

      UniProtKB/TrEMBL
      A0A2K5JX37
      Related
      ENSCANP00000033424.1, ENSCANT00000056651.1
      Conserved Domains (4) summary
      smart00020
      Location:554 → 776
      Tryp_SPc; Trypsin-like serine protease
      smart00130
      Location:270 → 350
      KR; Kringle domain
      cd00108
      Location:448 → 530
      KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
      cd00129
      Location:99 → 182
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...

    2. XM_011927695.1 → XP_011783085.1  hepatocyte growth factor isoform X2

      UniProtKB/TrEMBL
      A0A2K5JX41
      Related
      ENSCANP00000033429.1, ENSCANT00000056656.1
      Conserved Domains (2) summary
      smart00130
      Location:210 → 289
      KR; Kringle domain
      cd00129
      Location:39 → 122
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...

    3. XM_011927696.1 → XP_011783086.1  hepatocyte growth factor isoform X3

      Conserved Domains (2) summary
      smart00130
      Location:205 → 284
      KR; Kringle domain
      cd00129
      Location:39 → 122
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...
    Nucleotide Protein
    Heading Accession and Version

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