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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011698.1 RefSeqGene
- Range
-
5001..1118014
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001291997.2 → NP_001278926.1 WW domain-containing oxidoreductase isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in its 5' UTR and uses a downstream start codon, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AF211943
- UniProtKB/TrEMBL
-
B4DPG3
- Conserved Domains (2) summary
-
- cd09809
Location:11 → 294
- human_WWOX_like_SDR_c-like; human WWOX (WW domain-containing oxidoreductase)-like, classical (c)-like SDRs
- PRK06196
Location:2 → 291
- PRK06196; oxidoreductase; Provisional
-
NM_016373.4 → NP_057457.1 WW domain-containing oxidoreductase isoform 1
See identical proteins and their annotated locations for NP_057457.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AF211943
- Consensus CDS
-
CCDS42196.1
- UniProtKB/Swiss-Prot
- A8K323, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5, Q9NZC7
- UniProtKB/TrEMBL
- A0A411HBC7, A8K5I5, B3KNJ9
- Related
- ENSP00000457230.1, ENST00000566780.6
- Conserved Domains (2) summary
-
- cd09809
Location:124 → 407
- human_WWOX_like_SDR_c-like; human WWOX (WW domain-containing oxidoreductase)-like, classical (c)-like SDRs
- cd00201
Location:19 → 47
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
-
NM_130791.5 → NP_570607.1 WW domain-containing oxidoreductase isoform 2
See identical proteins and their annotated locations for NP_570607.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks several exons and uses an alternate 3'-terminal exon, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AF187015, DB035405
- Consensus CDS
-
CCDS42197.1
- UniProtKB/TrEMBL
-
A0A411HBF5
- Related
- ENSP00000348119.3, ENST00000355860.7
- Conserved Domains (3) summary
-
- cd00201
Location:60 → 90
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- pfam00397
Location:18 → 47
- WW; WW domain
- cl21454
Location:124 → 172
- NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
RNA
-
NR_120435.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) is intronless and extends past a splice site that is used in variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
- Source sequence(s)
-
AF227529, AW874693, DB035405
- Related
-
ENST00000569818.1
-
NR_120436.3 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses an alternate splice site in the 5'-terminal exon, lacks several exons, and uses an alternate 3'-terminal exon, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
- Source sequence(s)
-
AF187015, BU157392, DB035405
- Related
-
ENST00000563358.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000016.10 Reference GRCh38.p14 Primary Assembly
- Range
-
78099654..79212667
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060940.1 Alternate T2T-CHM13v2.0
- Range
-
84155399..85268915
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_018560.4: Suppressed sequence
- Description
- NM_018560.4: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
-
NM_130788.1: Suppressed sequence
- Description
- NM_130788.1: This RefSeq was permanently suppressed because it appears to be specific to a disease state.
-
NM_130790.1: Suppressed sequence
- Description
- NM_130790.1: This RefSeq was permanently suppressed because it appears to be specific to a disease state.
-
NM_130792.1: Suppressed sequence
- Description
- NM_130792.1: This RefSeq was permanently suppressed because it appears to be specific to a disease state.
-
NM_130844.2: Suppressed sequence
- Description
- NM_130844.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.