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    Lrrc31 leucine rich repeat containing 31 [ Mus musculus (house mouse) ]

    Gene ID: 320352, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Lrrc31provided by MGI
    Official Full Name
    leucine rich repeat containing 31provided by MGI
    Primary source
    MGI:MGI:2443864
    See related
    Ensembl:ENSMUSG00000074653 AllianceGenome:MGI:2443864
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E230002P03Rik
    Summary
    Orthologous to human LRRC31 (leucine rich repeat containing 31). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in large intestine adult (RPKM 2.8), colon adult (RPKM 2.6) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc31 in Genome Data Viewer
    Location:
    3 A3; 3 14.27 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (30732703..30753992, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (30678554..30699843, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:30500978-30501161 Neighboring gene myoneurin Neighboring gene leucine rich repeat containing 34 Neighboring gene STARR-seq mESC enhancer starr_07297 Neighboring gene STARR-seq mESC enhancer starr_07298 Neighboring gene leucine-rich repeats and IQ motif containing 4 Neighboring gene STARR-seq mESC enhancer starr_07299 Neighboring gene predicted gene 15462 Neighboring gene STARR-seq mESC enhancer starr_07301 Neighboring gene sterile alpha motif domain containing 7 Neighboring gene predicted gene, 33590 Neighboring gene SEC62 homolog, preprotein translocation

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 31

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001309233.1 → NP_001296162.1  leucine-rich repeat-containing protein 31

      Status: VALIDATED

      Source sequence(s)
      AC120377, AK136409, BB704012, CJ052990
      UniProtKB/TrEMBL
      F6VYM1
      Related
      ENSMUSP00000120802.4, ENSMUST00000126658.9
      Conserved Domains (3) summary
      COG4886
      Location:50 → 368
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00116
      Location:86 → 356
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:67 → 87
      LRR_RI; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      30732703..30753992 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319611.2 → XP_017175100.1  leucine-rich repeat-containing protein 31 isoform X2

      Conserved Domains (2) summary
      sd00033
      Location:75 → 95
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:64 → 331
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_017319610.2 → XP_017175099.1  leucine-rich repeat-containing protein 31 isoform X1

      Conserved Domains (2) summary
      sd00033
      Location:75 → 95
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:64 → 331
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_017319612.2 → XP_017175101.1  leucine-rich repeat-containing protein 31 isoform X3

      Conserved Domains (2) summary
      sd00033
      Location:48 → 74
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:88 → 415
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_177141.2: Suppressed sequence

      Description
      NM_177141.2: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

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