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    kif22.S kinesin family member 22 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100337510, updated on 27-Dec-2024

    Summary

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    Official Symbol
    kif22.S
    Official Full Name
    kinesin family member 22 S homeolog
    Primary source
    Xenbase:XB-GENE-979894
    Locus tag
    XELAEV_18002272mg
    See related
    EnsemblRapid:ENSXLAG00005005194 AllianceGenome:Xenbase:XB-GENE-979894
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    kid; obp; Xkid; kid-a; knsl4; obp-1; obp-2; kiff22; kif22-a; kif22-b; kiff22a; kiff22.S
    Summary
    Predicted to enable several functions, including ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to act upstream of or within microtubule-based movement. Predicted to be located in cytoplasm; microtubule; and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kif22.S in Genome Data Viewer
    Location:
    chromosome: 9_10S
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (115158828..115169191, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694820.1 (1928178..1938492)

    Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene MYC associated zinc finger protein S homeolog Neighboring gene uncharacterized LOC121399053 Neighboring gene PAXIP1 associated glutamate-rich protein 1 S homeolog Neighboring gene major vault protein S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway. Castro A, et al. Mol Cell Biol, 2003 Jun. PMID 12773557, Free PMC Article
    2. Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes. Perez LH, et al. Nat Cell Biol, 2002 Oct. PMID 12360284
    3. The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement. Funabiki H, et al. Cell, 2000 Aug 18. PMID 10966104
    4. Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Antonio C, et al. Cell, 2000 Aug 18. PMID 10966105
    5. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Zou H, et al. Science, 1999 Jul 16. PMID 10411507

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC79884

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    kinesin-like protein KIF22-A
    Names
    chromokinesin kid-a
    kinesin family member 22 a
    xkid-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001171977.1 → NP_001165448.1  kinesin-like protein KIF22-A

      See identical proteins and their annotated locations for NP_001165448.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ249840
      UniProtKB/Swiss-Prot
      Q6GPG0, Q7ZYL5, Q9I869, Q9I8K0, Q9I9A8
      Related
      ENSXLAP00005015339.1, ENSXLAT00005015620.1
      Conserved Domains (4) summary
      smart00129
      Location:31 → 365
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01376
      Location:31 → 357
      KISc_KID_like; Kinesin motor domain, KIF22/Kid-like subgroup
      pfam12836
      Location:588 → 642
      HHH_3; Helix-hairpin-helix motif
      cl21478
      Location:439 → 488
      ATP-synt_B; ATP synthase B/B' CF(0)

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      115158828..115169191 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I869.1 GenPept UniProtKB/Swiss-Prot:Q9I869

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