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    Insc INSC spindle orientation adaptor protein [ Chinchilla lanigera (long-tailed chinchilla) ]

    Gene ID: 102026418, updated on 16-Nov-2024

    Summary

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    Gene symbol
    Insc
    Gene description
    INSC spindle orientation adaptor protein
    See related
    Ensembl:ENSCLAG00000017184 RGD:8977997
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Chinchilla lanigera
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Chinchillidae; Chinchilla
    Orthologs
    human mouse all
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    Genomic context

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    See Insc in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    101 current ChiLan1.0 (GCF_000276665.1) Unplaced Scaffold NW_004955414.1 (30181402..30282279)

    NW_004955414.1Genomic Context describing neighboring genes Neighboring gene calcitonin Neighboring gene calcitonin related polypeptide beta Neighboring gene uncharacterized LOC102026965 Neighboring gene SRY-box transcription factor 6 Neighboring gene ethylmalonyl-CoA decarboxylase pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004955414.1 Unplaced Scaffold Reference ChiLan1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytoskeletal anchor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apical protein localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in asymmetric cell division IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of mitotic spindle orientation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of asymmetric cell division IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical cortex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein inscuteable homolog
    Names
    inscuteable homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Chinchilla lanigera Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ChiLan1.0 Primary Assembly

    Genomic

    1. NW_004955414.1 Reference ChiLan1.0 Primary Assembly

      Range
      30181402..30282279
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013512094.1 → XP_013367548.1  protein inscuteable homolog isoform X1

      UniProtKB/TrEMBL
      A0A8C2W751
      Related
      ENSCLAP00000025034.1, ENSCLAT00000025278.1
      Conserved Domains (2) summary
      cd00020
      Location:407 → 515
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam16748
      Location:23 → 66
      INSC_LBD; Inscuteable LGN-binding domain

    2. XM_013512096.1 → XP_013367550.1  protein inscuteable homolog isoform X2

      Conserved Domains (2) summary
      cd00020
      Location:376 → 484
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam16748
      Location:1 → 35
      INSC_LBD; Inscuteable LGN-binding domain
    Nucleotide Protein
    Heading Accession and Version

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