NCOA2 nuclear receptor coactivator 2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: NCOA2provided by HGNC
Official Full Name: nuclear receptor coactivator 2provided by HGNC
Primary source: HGNC:HGNC:7669
See related: Ensembl:ENSG00000140396 MIM:601993; AllianceGenome:HGNC:7669
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: SRC2; TIF2; GRIP1; KAT13C; NCoA-2; bHLHe75
Summary: The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Annotation information: Note: GRIP1 (Gene ID: 23426) and NCOA2 (Gene ID: 10499) share the GRIP1 symbol/alias in common. GRIP1 is a widely used alternative name for nuclear receptor coactivator 2 (NCOA2), which can be confused with the official symbol for glutamate receptor-interacting protein 1 (GRIP1). [06 Jul 2018]
Expression: Ubiquitous expression in testis (RPKM 5.6), esophagus (RPKM 4.0) and 25 other tissues See more
Orthologs: mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 8q13.3

Exon count:: 35

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	8	NC_000008.11 (70109782..70456446, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	8	NC_060932.1 (70539621..70834144, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	8	NC_000008.10 (71022017..71316452, complement)

Chromosome 8 - NC_000008.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Myxoid epithelioid smooth muscle tumor of the vulva: A distinct entity with MEF2D::NCOA2 gene fusion.
Title: Myxoid epithelioid smooth muscle tumor of the vulva: A distinct entity with MEF2D::NCOA2 gene fusion.
VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis.
Title: VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis.
A GRIP-1-EZH2 switch binding to GATA-4 is linked to the genesis of rhabdomyosarcoma through miR-29a.
Title: A GRIP-1-EZH2 switch binding to GATA-4 is linked to the genesis of rhabdomyosarcoma through miR-29a.
ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells.
Title: ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells.
Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts.
Title: Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts.
Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR).
Title: Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR).
Establishment and Characterization of a Cell Line (S-RMS1) Derived from an Infantile Spindle Cell Rhabdomyosarcoma with SRF-NCOA2 Fusion Transcript.
Title: Establishment and Characterization of a Cell Line (S-RMS1) Derived from an Infantile Spindle Cell Rhabdomyosarcoma with SRF-NCOA2 Fusion Transcript.
PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2.
Title: PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2.
Knockdown of NCOA2 Inhibits the Growth and Progression of Gastric Cancer by Affecting the Wnt Signaling Pathway-Related Protein Expression.
Title: Knockdown of NCOA2 Inhibits the Growth and Progression of Gastric Cancer by Affecting the Wnt Signaling Pathway-Related Protein Expression.
Our results demonstrate uterine tumor resembling ovarian sex-cord tumors are defined by recurrent fusions involving NCOA2 or NCOA3
Title: Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Distinct Entity Characterized by Recurrent NCOA2/3 Gene Fusions.

Submit: New GeneRIF Correction See all GeneRIFs (97)

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. EBI GWAS Catalog EBI GWAS CatalogPubMed
Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

Go to the top of the page Help

Protein interactions

Protein	Gene	Interaction	Pubs
Tat	tat	HIV-1 Tat may function as an adaptor molecule, efficiently stimulating the processes of transcription initiation and elongation through potentiation of the coupling of p160 co-activators and the P-TEFb complex	PubMed
	tat	The p160 nuclear receptor co-activator GRIP1 binds to the N-terminal region of HIV-1 Tat (amino acids 1-40) through its basic helix-loop-helix domain (amino acids 1-97) and enhances the transactivating activity of Tat	PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

D8S2130 (e-PCR)
- UniSTS:12801

STS-H93122 (e-PCR)
- UniSTS:48130

PMC170950P3 (e-PCR)
- UniSTS:271621

NCOA2_3768 (e-PCR)
- UniSTS:462368

SHGC-58132 (e-PCR)
- UniSTS:53056

RH91396 (e-PCR)
- UniSTS:85096

RH12853 (e-PCR)
- UniSTS:66694

A006O24 (e-PCR)
- UniSTS:62896

STS-X97674 (e-PCR)
- UniSTS:21172

RH123810 (e-PCR)
- UniSTS:136131

SHGC-142567 (e-PCR)
- UniSTS:174042

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables aryl hydrocarbon receptor binding	IPI Inferred from Physical Interaction more info	PubMed
enables chromatin binding	IEA Inferred from Electronic Annotation more info
enables nuclear receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables nuclear receptor binding	IPI Inferred from Physical Interaction more info	PubMed
enables nuclear receptor coactivator activity	IBA Inferred from Biological aspect of Ancestor more info
enables nuclear receptor coactivator activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info
enables protein domain specific binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription coactivator activity	ISS Inferred from Sequence or Structural Similarity more info
enables transcription coactivator activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to Thyroglobulin triiodothyronine	IEA Inferred from Electronic Annotation more info
involved_in cellular response to hormone stimulus	IBA Inferred from Biological aspect of Ancestor more info
involved_in circadian regulation of gene expression	ISS Inferred from Sequence or Structural Similarity more info
involved_in locomotor rhythm	IEA Inferred from Electronic Annotation more info
involved_in mRNA transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
involved_in mRNA transcription by RNA polymerase II	NAS Non-traceable Author Statement more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in peroxisome proliferator activated receptor signaling pathway	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of adipose tissue development	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of DNA-templated transcription	NAS Non-traceable Author Statement more info	PubMed
involved_in regulation of cellular response to insulin stimulus	NAS Non-traceable Author Statement more info	PubMed
involved_in regulation of glucose metabolic process	IEA Inferred from Electronic Annotation more info
involved_in regulation of lipid metabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to progesterone	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of RNA polymerase II transcription regulator complex	EXP Inferred from Experiment more info	PubMed
part_of RNA polymerase II transcription regulator complex	NAS Non-traceable Author Statement more info	PubMed
located_in chromatin	ISA Inferred from Sequence Alignment more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nuclear body	IDA Inferred from Direct Assay more info
located_in nucleoplasm	IDA Inferred from Direct Assay more info
located_in nucleoplasm	TAS Traceable Author Statement more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	NAS Non-traceable Author Statement more info	PubMed
part_of protein-containing complex	IMP Inferred from Mutant Phenotype more info	PubMed
part_of transcription regulator complex	IPI Inferred from Physical Interaction more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: nuclear receptor coactivator 2

Names: class E basic helix-loop-helix protein 75; glucocorticoid receptor-interacting protein-1; p160 steroid receptor coactivator 2; transcriptional intermediary factor 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001321703.2 → NP_001308632.1 nuclear receptor coactivator 2 isoform a

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1, 2 and 3 all encode isoform a.

Source sequence(s)

AC022730, AW504723, BC047111, CB270668, CK903771, CN291204, DA691975, X97674

Consensus CDS

CCDS47872.1

UniProtKB/Swiss-Prot

Q14CD2, Q15596

Conserved Domains (10) summary

smart00353
Location:35 → 88

HLH; helix loop helix domain

cd00130
Location:123 → 213

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam07469
Location:1281 → 1338

DUF1518; Domain of unknown function (DUF1518)

pfam08815
Location:1071 → 1116

Nuc_rec_co-act; Nuclear receptor coactivator

pfam08832
Location:640 → 709

SRC-1; Steroid receptor coactivator

pfam09606
Location:892 → 1372

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

pfam14598
Location:268 → 378

PAS_11; PAS domain

pfam16279
Location:731 → 816

DUF4927; Domain of unknown function (DUF4927)

pfam16665
Location:463 → 587

NCOA_u2; Unstructured region on nuclear receptor coactivator protein

cl26950
Location:1269 → 1399

LsmAD; LsmAD domain
NM_001321707.2 → NP_001308636.1 nuclear receptor coactivator 2 isoform a

Status: REVIEWED

Description

Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode isoform a.

Source sequence(s)

AC022730, AW504723, BC047111, CB270668, CK903771, CN291204, DA691975, X97674

Consensus CDS

CCDS47872.1

UniProtKB/Swiss-Prot

Q14CD2, Q15596

Conserved Domains (10) summary

smart00353
Location:35 → 88

HLH; helix loop helix domain

cd00130
Location:123 → 213

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam07469
Location:1281 → 1338

DUF1518; Domain of unknown function (DUF1518)

pfam08815
Location:1071 → 1116

Nuc_rec_co-act; Nuclear receptor coactivator

pfam08832
Location:640 → 709

SRC-1; Steroid receptor coactivator

pfam09606
Location:892 → 1372

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

pfam14598
Location:268 → 378

PAS_11; PAS domain

pfam16279
Location:731 → 816

DUF4927; Domain of unknown function (DUF4927)

pfam16665
Location:463 → 587

NCOA_u2; Unstructured region on nuclear receptor coactivator protein

cl26950
Location:1269 → 1399

LsmAD; LsmAD domain
NM_001321711.2 → NP_001308640.1 nuclear receptor coactivator 2 isoform b

Status: REVIEWED

Description

Transcript Variant: This variant (4) differs in the 5' UTR and lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform 1. Both variants 4 and 5 encode isoform b.

Source sequence(s)

AK298528, AL712418, AW504723, BC047111, CB270668, CK903771, CN291204, DA691975, X97674

UniProtKB/Swiss-Prot

Q15596

UniProtKB/TrEMBL

B4DPW8

Conserved Domains (9) summary

smart00353
Location:35 → 88

HLH; helix loop helix domain

cd00130
Location:123 → 213

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00989
Location:119 → 215

PAS; PAS fold

pfam07469
Location:1212 → 1269

DUF1518; Domain of unknown function (DUF1518)

pfam08815
Location:1002 → 1047

Nuc_rec_co-act; Nuclear receptor coactivator

pfam08832
Location:640 → 709

SRC-1; Steroid receptor coactivator

pfam14598
Location:268 → 378

PAS_11; PAS domain

pfam16279
Location:731 → 816

DUF4927; Domain of unknown function (DUF4927)

pfam16665
Location:463 → 587

NCOA_u2; Unstructured region on nuclear receptor coactivator protein
NM_001321712.2 → NP_001308641.1 nuclear receptor coactivator 2 isoform b

Status: REVIEWED

Description

Transcript Variant: This variant (5) differs in the 5' UTR and lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform 1. Both variants 4 and 5 encode isoform b.

Source sequence(s)

AC022730, AK298528, AW504723, BC047111, CB270668, CK002637, CK903771, CN291204, DA691975, X97674

UniProtKB/Swiss-Prot

Q15596

UniProtKB/TrEMBL

B4DPW8

Conserved Domains (9) summary

smart00353
Location:35 → 88

HLH; helix loop helix domain

cd00130
Location:123 → 213

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00989
Location:119 → 215

PAS; PAS fold

pfam07469
Location:1212 → 1269

DUF1518; Domain of unknown function (DUF1518)

pfam08815
Location:1002 → 1047

Nuc_rec_co-act; Nuclear receptor coactivator

pfam08832
Location:640 → 709

SRC-1; Steroid receptor coactivator

pfam14598
Location:268 → 378

PAS_11; PAS domain

pfam16279
Location:731 → 816

DUF4927; Domain of unknown function (DUF4927)

pfam16665
Location:463 → 587

NCOA_u2; Unstructured region on nuclear receptor coactivator protein
NM_001321713.2 → NP_001308642.1 nuclear receptor coactivator 2 isoform c

Status: REVIEWED

Description

Transcript Variant: This variant (6) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a.

Source sequence(s)

AC022730, AW504723, BC047111, CB270668, CK002637, CK903771, CN291204, DA691975, X97674

UniProtKB/Swiss-Prot

Q15596

Conserved Domains (6) summary

pfam07469
Location:1127 → 1184

DUF1518; Domain of unknown function (DUF1518)

pfam08815
Location:917 → 962

Nuc_rec_co-act; Nuclear receptor coactivator

pfam08832
Location:486 → 555

SRC-1; Steroid receptor coactivator

pfam14598
Location:114 → 224

PAS_11; PAS domain

pfam16279
Location:577 → 662

DUF4927; Domain of unknown function (DUF4927)

pfam16665
Location:309 → 433

NCOA_u2; Unstructured region on nuclear receptor coactivator protein
NM_006540.4 → NP_006531.1 nuclear receptor coactivator 2 isoform a

See identical proteins and their annotated locations for NP_006531.1

Status: REVIEWED

Description

Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode isoform a.

Source sequence(s)

AL712418, AW504723, BC047111, CB270668, CK903771, CN291204, DA691975, X97674

Consensus CDS

CCDS47872.1

UniProtKB/Swiss-Prot

Q14CD2, Q15596

Related

ENSP00000399968.2, ENST00000452400.7

Conserved Domains (10) summary

smart00353
Location:35 → 88

HLH; helix loop helix domain

cd00130
Location:123 → 213

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam07469
Location:1281 → 1338

DUF1518; Domain of unknown function (DUF1518)

pfam08815
Location:1071 → 1116

Nuc_rec_co-act; Nuclear receptor coactivator

pfam08832
Location:640 → 709

SRC-1; Steroid receptor coactivator

pfam09606
Location:892 → 1372

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

pfam14598
Location:268 → 378

PAS_11; PAS domain

pfam16279
Location:731 → 816

DUF4927; Domain of unknown function (DUF4927)

pfam16665
Location:463 → 587

NCOA_u2; Unstructured region on nuclear receptor coactivator protein

cl26950
Location:1269 → 1399

LsmAD; LsmAD domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000008.11 Reference GRCh38.p14 Primary Assembly

Range

70109782..70456446 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047421240.1 → XP_047277196.1 nuclear receptor coactivator 2 isoform X1
XM_047421258.1 → XP_047277214.1 nuclear receptor coactivator 2 isoform X4
XM_047421256.1 → XP_047277212.1 nuclear receptor coactivator 2 isoform X3
XM_017012963.3 → XP_016868452.1 nuclear receptor coactivator 2 isoform X1
XM_047421233.1 → XP_047277189.1 nuclear receptor coactivator 2 isoform X1
XM_047421262.1 → XP_047277218.1 nuclear receptor coactivator 2 isoform X4
XM_047421247.1 → XP_047277203.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_047421234.1 → XP_047277190.1 nuclear receptor coactivator 2 isoform X1
XM_047421254.1 → XP_047277210.1 nuclear receptor coactivator 2 isoform X3
XM_017012961.3 → XP_016868450.1 nuclear receptor coactivator 2 isoform X1
XM_047421249.1 → XP_047277205.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_047421261.1 → XP_047277217.1 nuclear receptor coactivator 2 isoform X4
XM_047421244.1 → XP_047277200.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_017012966.3 → XP_016868455.1 nuclear receptor coactivator 2 isoform X1
XM_047421241.1 → XP_047277197.1 nuclear receptor coactivator 2 isoform X1
XM_047421259.1 → XP_047277215.1 nuclear receptor coactivator 2 isoform X4
XM_047421255.1 → XP_047277211.1 nuclear receptor coactivator 2 isoform X3
XM_047421230.1 → XP_047277186.1 nuclear receptor coactivator 2 isoform X1
XM_047421237.1 → XP_047277193.1 nuclear receptor coactivator 2 isoform X1
XM_047421251.1 → XP_047277207.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_017012968.3 → XP_016868457.1 nuclear receptor coactivator 2 isoform X1
XM_047421257.1 → XP_047277213.1 nuclear receptor coactivator 2 isoform X3
XM_047421243.1 → XP_047277199.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_017012962.3 → XP_016868451.1 nuclear receptor coactivator 2 isoform X1
XM_047421252.1 → XP_047277208.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_047421250.1 → XP_047277206.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_047421236.1 → XP_047277192.1 nuclear receptor coactivator 2 isoform X1
XM_047421260.1 → XP_047277216.1 nuclear receptor coactivator 2 isoform X4
XM_047421245.1 → XP_047277201.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_017012964.3 → XP_016868453.1 nuclear receptor coactivator 2 isoform X1
XM_047421232.1 → XP_047277188.1 nuclear receptor coactivator 2 isoform X1
XM_047421239.1 → XP_047277195.1 nuclear receptor coactivator 2 isoform X1
XM_047421242.1 → XP_047277198.1 nuclear receptor coactivator 2 isoform X1
XM_047421235.1 → XP_047277191.1 nuclear receptor coactivator 2 isoform X1
XM_047421246.1 → XP_047277202.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_047421264.1 → XP_047277220.1 nuclear receptor coactivator 2 isoform X4
XM_047421253.1 → XP_047277209.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_017012971.3 → XP_016868460.1 nuclear receptor coactivator 2 isoform X1
XM_017012970.3 → XP_016868459.1 nuclear receptor coactivator 2 isoform X1
XM_047421263.1 → XP_047277219.1 nuclear receptor coactivator 2 isoform X4
XM_047421248.1 → XP_047277204.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_017012969.3 → XP_016868458.1 nuclear receptor coactivator 2 isoform X1
XM_017012972.3 → XP_016868461.1 nuclear receptor coactivator 2 isoform X5

Alternate T2T-CHM13v2.0

Genomic

NC_060932.1 Alternate T2T-CHM13v2.0

Range

70539621..70834144 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054359579.1 → XP_054215554.1 nuclear receptor coactivator 2 isoform X4
XM_054359577.1 → XP_054215552.1 nuclear receptor coactivator 2 isoform X3
XM_054359548.1 → XP_054215523.1 nuclear receptor coactivator 2 isoform X1
XM_054359554.1 → XP_054215529.1 nuclear receptor coactivator 2 isoform X1
XM_054359583.1 → XP_054215558.1 nuclear receptor coactivator 2 isoform X4
XM_054359568.1 → XP_054215543.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359555.1 → XP_054215530.1 nuclear receptor coactivator 2 isoform X1
XM_054359575.1 → XP_054215550.1 nuclear receptor coactivator 2 isoform X3
XM_054359547.1 → XP_054215522.1 nuclear receptor coactivator 2 isoform X1
XM_054359570.1 → XP_054215545.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359582.1 → XP_054215557.1 nuclear receptor coactivator 2 isoform X4
XM_054359565.1 → XP_054215540.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359551.1 → XP_054215526.1 nuclear receptor coactivator 2 isoform X1
XM_054359562.1 → XP_054215537.1 nuclear receptor coactivator 2 isoform X1
XM_054359580.1 → XP_054215555.1 nuclear receptor coactivator 2 isoform X4
XM_054359576.1 → XP_054215551.1 nuclear receptor coactivator 2 isoform X3
XM_054359550.1 → XP_054215525.1 nuclear receptor coactivator 2 isoform X1
XM_054359561.1 → XP_054215536.1 nuclear receptor coactivator 2 isoform X1
XM_054359572.1 → XP_054215547.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359560.1 → XP_054215535.1 nuclear receptor coactivator 2 isoform X1
XM_054359578.1 → XP_054215553.1 nuclear receptor coactivator 2 isoform X3
XM_054359564.1 → XP_054215539.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359549.1 → XP_054215524.1 nuclear receptor coactivator 2 isoform X1
XM_054359573.1 → XP_054215548.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359571.1 → XP_054215546.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359557.1 → XP_054215532.1 nuclear receptor coactivator 2 isoform X1
XM_054359581.1 → XP_054215556.1 nuclear receptor coactivator 2 isoform X4
XM_054359566.1 → XP_054215541.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359558.1 → XP_054215533.1 nuclear receptor coactivator 2 isoform X1
XM_054359552.1 → XP_054215527.1 nuclear receptor coactivator 2 isoform X1
XM_054359556.1 → XP_054215531.1 nuclear receptor coactivator 2 isoform X1
XM_054359567.1 → XP_054215542.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359559.1 → XP_054215534.1 nuclear receptor coactivator 2 isoform X1
XM_054359585.1 → XP_054215560.1 nuclear receptor coactivator 2 isoform X4
XM_054359574.1 → XP_054215549.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359563.1 → XP_054215538.1 nuclear receptor coactivator 2 isoform X1
XM_054359553.1 → XP_054215528.1 nuclear receptor coactivator 2 isoform X1
XM_054359584.1 → XP_054215559.1 nuclear receptor coactivator 2 isoform X4
XM_054359569.1 → XP_054215544.1 nuclear receptor coactivator 2 isoform X2

UniProtKB/Swiss-Prot

Q14CD2, Q15596
XM_054359586.1 → XP_054215561.1 nuclear receptor coactivator 2 isoform X5