U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from OMIM

    • Showing Current items.

    MRGPRX4 MAS related GPR family member X4 [ Homo sapiens (human) ]

    Gene ID: 117196, updated on 27-Nov-2024

    Summary

    Official Symbol
    MRGPRX4provided by HGNC
    Official Full Name
    MAS related GPR family member X4provided by HGNC
    Primary source
    HGNC:HGNC:17617
    See related
    Ensembl:ENSG00000179817 MIM:607230; AllianceGenome:HGNC:17617
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GPCR; MRGX4; SNSR6
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See MRGPRX4 in Genome Data Viewer
    Location:
    11p15.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (18172837..18174280)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (18268336..18269779)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (18194384..18195827)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene MAS related GPR family member X3 Neighboring gene MAS related GPR family member X12, pseudogene Neighboring gene glycolipid transfer protein pseudogene 1 Neighboring gene MAS related GPR family member X13, pseudogene

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC129753, MGC129754

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    mas-related G-protein coupled receptor member X4
    Names
    G protein-coupled receptor MRGX4
    G protein-coupled receptor SNSR5
    G protein-coupled receptor SNSR6
    MAS-related GPR, member X4
    Mas-related G protein-coupled receptor X4
    sensory neuron-specific G-protein coupled receptor 5/6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_054032.3NP_473373.2  mas-related G-protein coupled receptor member X4

      See identical proteins and their annotated locations for NP_473373.2

      Status: VALIDATED

      Source sequence(s)
      AC090099, BC095509, CN835944
      Consensus CDS
      CCDS7831.1
      UniProtKB/Swiss-Prot
      Q3KNU3, Q3KNU4, Q502W0, Q8TDD6, Q8TDD7, Q96LA9
      UniProtKB/TrEMBL
      A0A2I4R868
      Related
      ENSP00000314042.3, ENST00000314254.3
      Conserved Domains (1) summary
      pfam00001
      Location:44272
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      18172837..18174280
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      18268336..18269779
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)