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    ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B [ Homo sapiens (human) ]

    Gene ID: 56899, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ANKS1Bprovided by HGNC
    Official Full Name
    ankyrin repeat and sterile alpha motif domain containing 1Bprovided by HGNC
    Primary source
    HGNC:HGNC:24600
    See related
    Ensembl:ENSG00000185046 MIM:607815; AllianceGenome:HGNC:24600
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    EB1; AIDA; EB-1; ANKS2; AIDA-1; cajalin-2
    Summary
    This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
    Expression
    Broad expression in brain (RPKM 8.0), thyroid (RPKM 1.1) and 21 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ANKS1B in Genome Data Viewer
    Location:
    12q23.1
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (98734786..99984936, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (98707730..99946157, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (99128564..100378714, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene MPRA-validated peak1907 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4754 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_31387 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:99037284-99037911 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:99037912-99038538 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:99038539-99039166 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4756 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr12:99043141-99044340 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:99072005-99072576 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_31421 Neighboring gene solute carrier family 25 member 3 Neighboring gene small nucleolar RNA, H/ACA box 53 Neighboring gene MPRA-validated peak1909 silencer Neighboring gene IKBKB interacting protein Neighboring gene ReSE screen-validated silencer GRCh37_chr12:99187754-99187963 Neighboring gene apoptotic peptidase activating factor 1 Neighboring gene probable ribosome biogenesis protein RLP24 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_31455 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:99250207-99250805 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr12:99250806-99251403 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:99254871-99255612 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:99288347-99288846 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:99303485-99304033 Neighboring gene Sharpr-MPRA regulatory region 15444 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_31475 Neighboring gene uncharacterized LOC101928937 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:99502667-99503267 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6849 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6850 Neighboring gene RNA, 5S ribosomal pseudogene 366 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:99548399-99548898 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_31500 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4758 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:99848949-99849450 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:99849451-99849950 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4759 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:100064333-100064865 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:100074143-100074643 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr12:100117017-100117569 Neighboring gene golgi associated RAB2 interactor family member 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:100377744-100378574 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4760 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:100414790-100414953 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4761 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:100536197-100536960 Neighboring gene ribosomal protein S4X pseudogene 1 Neighboring gene bridge-like lipid transfer protein family member 3B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells. Kislova AV, et al. Chromosome Res, 2023 Aug 19. PMID 37597021
    2. EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1. Fu X, et al. Oncogene, 1999 Sep 2. PMID 10490826
    3. Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia. Wiemels JL, et al. Proc Natl Acad Sci U S A, 2002 Nov 12. PMID 12415113, Free PMC Article
    4. A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import. Kurabi A, et al. J Mol Biol, 2009 Oct 9. PMID 19666031
    5. The genetic background difference between diabetic patients with and without nephropathy in a Taiwanese population by linkage disequilibrium mapping using 382 autosomal STR markers. Pei D, et al. Genet Test Mol Biomarkers, 2010 Jun. PMID 20578947

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
      Title: AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
    2. Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells.
      Title: Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells.
    3. Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma.
      Title: Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma.
    4. Circular RNA circANKS1B acts as a sponge for miR-152-3p and promotes prostate cancer progression by upregulating TGF-alpha expression.
      Title: Circular RNA circANKS1B acts as a sponge for miR-152-3p and promotes prostate cancer progression by upregulating TGF-α expression.
    5. Study describe monogenic copy-number variations in ANKS1B in individuals that display a previously undefined spectrum of neurodevelopmental phenotypes that authors term ANKS1B haploinsufficiency syndrome.
      Title: Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.
    6. Our data uncover an essential role of the novel circular RNA circANKS1B in the metastasis of breast cancer, which demonstrate that therapeutic targeting of circANKS1B may better prevent breast cancer metastasis.
      Title: The pro-metastasis effect of circANKS1B in breast cancer.
    7. this is the first genetic association study of the relationship between the rs7968606 SNP of ANKS1B and the response of schizophrenia patients to treatment with amisulpride.
      Title: rs7968606 polymorphism of ANKS1B is associated with improvement in the PANSS general score of schizophrenia caused by amisulpride.
    8. We provide the first evidence that ANKS1B expression is down regulated in ccRCC tumors relative to patient-matched normal kidney tissue in smokers.
      Title: ANKS1B is a smoking-related molecular alteration in clear cell renal cell carcinoma.
    9. AIDA1 PTB domain binds amyloid protein precursorin a similar manner to the X11/Mint PTB domain.
      Title: Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein.
    10. Targeted-E2A-PBX1 inhibition leads to reduced expression of the EB-1 and Wnt16b genes; aberrant expression of these genes may be a key step in leukemogenesis in t(1;19)-positive pre-B leukemia.
      Title: The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line.
    Submit: New GeneRIF Correction See all GeneRIFs (24)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.
    EBI GWAS Catalog
    Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.
    EBI GWAS Catalog
    Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
    EBI GWAS Catalog
    Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
    EBI GWAS Catalog
    Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.
    EBI GWAS Catalog
    Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.
    EBI GWAS Catalog
    Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC26087

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ephrin receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ephrin receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ephrin receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Cajal body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		  
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat and sterile alpha motif domain-containing protein 1B
    Names
    E2a-Pbx1-associated protein
    amyloid-beta precursor protein intracellular domain associated protein 1
    cajalin 2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029860.2 RefSeqGene

      Range
      4719..1245681
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001204065.2 → NP_001190994.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform d

      See identical proteins and their annotated locations for NP_001190994.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (d) has a shorter N-terminus, a longer and distinct C-terminus, and an additional segment compared to isoform a.
      Source sequence(s)
      AK315954, BC150204, BP193713
      UniProtKB/TrEMBL
      B4DJA1, B7Z9I9
      Conserved Domains (1) summary
      cd01274
      Location:76 → 225
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    2. NM_001204066.2 → NP_001190995.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform e

      See identical proteins and their annotated locations for NP_001190995.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and coding region, in the 3' UTR and coding region, lacks an alternate in-frame segment, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (e) has a shorter N-terminus, a longer and distinct C-terminus, a missing segment, and an additional segment compared to isoform a.
      Source sequence(s)
      AC079954, BC026313, BC068451, BC150204
      Consensus CDS
      CCDS55865.1
      UniProtKB/Swiss-Prot
      Q7Z6G8
      Related
      ENSP00000447312.2, ENST00000549025.6
      Conserved Domains (2) summary
      cd01274
      Location:144 → 293
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:1 → 46
      SAM_superfamily; SAM (Sterile alpha motif )

    3. NM_001204067.2 → NP_001190996.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform f

      See identical proteins and their annotated locations for NP_001190996.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (f) has a shorter and distinct N-terminus, a longer and distinct C-terminus, and a missing segment compared to isoform a.
      Source sequence(s)
      AK294191, BC026313, BC068451, BC150204
      Consensus CDS
      CCDS55871.1
      UniProtKB/Swiss-Prot
      Q7Z6G8
      Related
      ENSP00000450015.1, ENST00000547446.5
      Conserved Domains (3) summary
      cd09499
      Location:6 → 72
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:77 → 141
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:181 → 330
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    4. NM_001204068.2 → NP_001190997.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform g

      See identical proteins and their annotated locations for NP_001190997.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and coding region and in the 3' UTR and coding region compared to variant 1. The resulting isoform (g, also known as AIDA-1a) has a shorter and distinct N-terminus and a shorter and distinct C-terminus compared to isoform a.
      Source sequence(s)
      AY281132, BC026313, BC142669, BC150204, DA690060
      Consensus CDS
      CCDS55869.1
      UniProtKB/Swiss-Prot
      Q7Z6G8
      Related
      ENSP00000447839.1, ENST00000546960.5
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:272 → 421
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    5. NM_001204069.2 → NP_001190998.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform h

      See identical proteins and their annotated locations for NP_001190998.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR and coding region, in the 3' UTR and coding region, lacks an alternate in-frame exon, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (h) has a shorter and distinct N-terminus, a longer and distinct C-terminus, a missing segment, and an additional segment compared to isoform a.
      Source sequence(s)
      BC150204, DA690060
      Consensus CDS
      CCDS55868.1
      UniProtKB/Swiss-Prot
      Q7Z6G8
      Related
      ENSP00000447999.2, ENST00000550693.6
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:236 → 385
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    6. NM_001204070.2 → NP_001190999.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform i

      See identical proteins and their annotated locations for NP_001190999.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (i, also known as AIDA-1c) has a shorter and distinct N-terminus, a longer and distinct C-terminus, and a missing segment compared to isoform a.
      Source sequence(s)
      AY753193, BC150204, DA690060
      Consensus CDS
      CCDS55867.1
      UniProtKB/Swiss-Prot
      Q7Z6G8
      Related
      ENSP00000448205.1, ENST00000546568.5
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:212 → 361
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    7. NM_001204079.2 → NP_001191008.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform j

      See identical proteins and their annotated locations for NP_001191008.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (j) has a shorter N-terminus, a longer and distinct C-terminus, and an additional segment compared to isoform a.
      Source sequence(s)
      AM980945, BC150204, BP193713
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:77 → 226
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    8. NM_001204080.2 → NP_001191009.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform k

      See identical proteins and their annotated locations for NP_001191009.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR and coding region and in the 3' UTR and coding region compared to variant 1. The resulting isoform (k) has a shorter and distinct N-terminus and a longer and distinct C-terminus compared to isoform a. Variants 11 and 39 both encode the same isoform (k).
      Source sequence(s)
      AC008126, AY356353, BC150204, BP193713
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:52 → 201
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    9. NM_001204081.2 → NP_001191010.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform l

      See identical proteins and their annotated locations for NP_001191010.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (l) has a shorter and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AC008126, AC011248, AK294994, BC142669, BP193713
      Consensus CDS
      CCDS55864.1
      UniProtKB/Swiss-Prot
      Q7Z6G8
      Related
      ENSP00000345510.6, ENST00000341752.11
      Conserved Domains (1) summary
      cd01274
      Location:52 → 201
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    10. NM_001352185.1 → NP_001339114.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform p

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
      Conserved Domains (5) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1046 → 1195
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    11. NM_001352186.2 → NP_001339115.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform m

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) represents the longest transcript and encodes the longest isoform (m).
      Source sequence(s)
      AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
      Consensus CDS
      CCDS91740.1
      UniProtKB/TrEMBL
      A0A804HKX1
      Related
      ENSP00000508105.1, ENST00000683438.2
      Conserved Domains (5) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1071 → 1220
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    12. NM_001352187.1 → NP_001339116.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform o

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
      Conserved Domains (5) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1046 → 1195
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    13. NM_001352188.1 → NP_001339117.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform n

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC048330, AC078916, AC079954, AC084374, AC117377, AC141554, AC141556
      Conserved Domains (5) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1070 → 1219
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    14. NM_001352189.1 → NP_001339118.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform v

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:6 → 72
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:77 → 141
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:265 → 414
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    15. NM_001352190.1 → NP_001339119.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform qq

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:6 → 72
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:77 → 141
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:266 → 415
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    16. NM_001352191.2 → NP_001339120.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ee

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09500
      Location:51 → 115
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:155 → 304
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:1 → 46
      SAM_superfamily; SAM (Sterile alpha motif )

    17. NM_001352192.2 → NP_001339121.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform z

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09500
      Location:51 → 115
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:215 → 364
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:1 → 46
      SAM_superfamily; SAM (Sterile alpha motif )

    18. NM_001352193.2 → NP_001339122.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform y

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Related
      ENSP00000448744.1, ENST00000550778.5
      Conserved Domains (3) summary
      cd09500
      Location:51 → 115
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:215 → 364
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:1 → 46
      SAM_superfamily; SAM (Sterile alpha motif )

    19. NM_001352194.2 → NP_001339123.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform cc

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd01274
      Location:176 → 325
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:108 → 152
      SAM_superfamily; SAM (Sterile alpha motif )

    20. NM_001352195.2 → NP_001339124.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform r

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:296 → 445
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    21. NM_001352196.2 → NP_001339125.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform s

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:296 → 445
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    22. NM_001352197.2 → NP_001339126.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform w

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:272 → 421
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    23. NM_001352198.2 → NP_001339127.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform q

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:297 → 446
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    24. NM_001352199.2 → NP_001339128.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform aa

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:212 → 361
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    25. NM_001352200.2 → NP_001339129.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform u

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:297 → 446
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    26. NM_001352201.2 → NP_001339130.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform dd

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd01274
      Location:176 → 325
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:108 → 152
      SAM_superfamily; SAM (Sterile alpha motif )

    27. NM_001352202.2 → NP_001339131.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform pp

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:272 → 421
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    28. NM_001352203.2 → NP_001339132.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform bb

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd01274
      Location:201 → 350
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:108 → 159
      SAM_superfamily; SAM (Sterile alpha motif )

    29. NM_001352204.2 → NP_001339133.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform t

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:272 → 421
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    30. NM_001352205.2 → NP_001339134.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform oo

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:297 → 446
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    31. NM_001352206.2 → NP_001339135.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform x

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248, AC079954, AC117377
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:236 → 385
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    32. NM_001352207.2 → NP_001339136.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform k

      Status: REVIEWED

      Description
      Transcript Variant: This variant (39), as well as variant 11, encodes isoform k.
      Source sequence(s)
      AC008126, AC011248
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:52 → 201
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    33. NM_001352208.2 → NP_001339137.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform gg

      Status: REVIEWED

      Description
      Transcript Variant: This variant (36), as well as variant 37, encodes isoform gg.
      Source sequence(s)
      AC008126, AC011248
      Consensus CDS
      CCDS86326.1
      UniProtKB/TrEMBL
      B4DJA1, F8VR14
      Conserved Domains (1) summary
      cd01274
      Location:76 → 225
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    34. NM_001352209.2 → NP_001339138.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ii

      Status: REVIEWED

      Description
      Transcript Variant: This variant (40), as well as variant 41, encodes isoform ii.
      Source sequence(s)
      AC008126, AC011248
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:52 → 201
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    35. NM_001352210.2 → NP_001339139.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform kk

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:27 → 176
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    36. NM_001352211.2 → NP_001339140.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

      Status: REVIEWED

      Description
      Transcript Variant: This variant (44), as well as variants 45, 46, 47, and 48, encodes isoform ll.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    37. NM_001352212.2 → NP_001339141.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

      Status: REVIEWED

      Description
      Transcript Variant: This variant (45), as well as variants 44, 46, 47, and 48, encodes isoform ll.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    38. NM_001352213.2 → NP_001339142.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform nn

      Status: REVIEWED

      Description
      Transcript Variant: This variant (50), as well as variants 51 and 52, encodes isoform nn.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    39. NM_001352214.2 → NP_001339143.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform nn

      Status: REVIEWED

      Description
      Transcript Variant: This variant (51), as well as variants 50 and 52, encodes isoform nn.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    40. NM_001352216.2 → NP_001339145.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform nn

      Status: REVIEWED

      Description
      Transcript Variant: This variant (52), as well as variants 50 and 51, encodes isoform nn.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    41. NM_001352217.2 → NP_001339146.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform mm

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    42. NM_001352218.2 → NP_001339147.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

      Status: REVIEWED

      Description
      Transcript Variant: This variant (46), as well as variants 44, 45, 47, and 48, encodes isoform ll.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    43. NM_001352219.2 → NP_001339148.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ff

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:77 → 226
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    44. NM_001352220.2 → NP_001339149.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

      Status: REVIEWED

      Description
      Transcript Variant: This variant (47), as well as variants 44, 45, 46, and 48, encodes isoform ll.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    45. NM_001352221.2 → NP_001339150.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ii

      Status: REVIEWED

      Description
      Transcript Variant: This variant (41), as well as variant 40, encodes isoform ii.
      Source sequence(s)
      AC008126, AC011248
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:52 → 201
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    46. NM_001352222.2 → NP_001339151.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform gg

      Status: REVIEWED

      Description
      Transcript Variant: This variant (37), as well as variant 36, encodes isoform gg.
      Source sequence(s)
      AC008126, AC011248
      Consensus CDS
      CCDS86326.1
      UniProtKB/TrEMBL
      B4DJA1, F8VR14
      Related
      ENSP00000331256.7, ENST00000333732.11
      Conserved Domains (1) summary
      cd01274
      Location:76 → 225
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    47. NM_001352223.2 → NP_001339152.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform hh

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:77 → 226
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    48. NM_001352224.2 → NP_001339153.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform ll

      Status: REVIEWED

      Description
      Transcript Variant: This variant (48), as well as variants 44, 45, 46, and 47, encodes isoform ll.
      Source sequence(s)
      AC008126, AC011248
      Conserved Domains (1) summary
      cd01274
      Location:1 → 126
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    49. NM_001352225.2 → NP_001339154.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform jj

      Status: REVIEWED

      Source sequence(s)
      AC008126, AC011248
      UniProtKB/TrEMBL
      B4DJA1
      Conserved Domains (1) summary
      cd01274
      Location:27 → 176
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    50. NM_020140.4 → NP_064525.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform c

      See identical proteins and their annotated locations for NP_064525.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and coding region and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) has a shorter and distinct N-terminus and lacks an alternate segment compared to isoform a.
      Source sequence(s)
      AC011248, AC117377, BC142669, DA690060
      Consensus CDS
      CCDS55866.1
      UniProtKB/Swiss-Prot
      Q7Z6G8
      Related
      ENSP00000448993.2, ENST00000549558.6
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:212 → 361
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    51. NM_152788.4 → NP_690001.3  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform a

      See identical proteins and their annotated locations for NP_690001.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform a (also known as AIDA-1b).
      Source sequence(s)
      AC011248, AK124453, AY281131, BC142669, DA183756, DA783474
      Consensus CDS
      CCDS55872.1
      UniProtKB/Swiss-Prot
      A5PKY5, A7E259, A8K153, A8MSN4, B4DFP6, B4DH98, F8VPM3, F8VZR9, F8WC27, Q5XLJ0, Q6IVB5, Q6NUS4, Q7Z6G6, Q7Z6G7, Q7Z6G8, Q8TAP3, Q9NRX7, Q9Y5K9
      Related
      ENSP00000449629.2, ENST00000547776.6
      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1046 → 1195
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    52. NM_181670.4 → NP_858056.2  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform b

      See identical proteins and their annotated locations for NP_858056.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding region, in the 3' UTR and coding region, and contains an alternate in-frame exon compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus, a longer and distinct C-terminus, and an additional segment compared to isoform a.
      Source sequence(s)
      BC026313, BC150204, DA690060
      Consensus CDS
      CCDS55870.1
      UniProtKB/TrEMBL
      H0YI72
      Related
      ENSP00000448203.2, ENST00000549493.6
      Conserved Domains (3) summary
      cd09499
      Location:37 → 103
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:108 → 172
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:296 → 445
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      98734786..99984936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006719514.5 → XP_006719577.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X11

      Conserved Domains (8) summary
      cd09499
      Location:807 → 873
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:878 → 942
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:804 → 869
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:982 → 1131
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    2. XM_006719507.5 → XP_006719570.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X4

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1071 → 1220
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    3. XM_005269029.6 → XP_005269086.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X6

      Conserved Domains (8) summary
      cd09499
      Location:807 → 873
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:878 → 942
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:804 → 869
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1042 → 1191
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    4. XM_017019652.3 → XP_016875141.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X3

    5. XM_006719513.5 → XP_006719576.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X10

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:986 → 1135
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    6. XM_006719512.5 → XP_006719575.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X9

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:986 → 1135
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    7. XM_011538571.4 → XP_011536873.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X7

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1037 → 1186
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    8. XM_006719504.5 → XP_006719567.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X1

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1070 → 1219
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    9. XM_006719505.5 → XP_006719568.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X2

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1071 → 1220
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    10. XM_047429165.1 → XP_047285121.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

    11. XM_024449061.2 → XP_024304829.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X14

      Conserved Domains (3) summary
      cd09499
      Location:443 → 509
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:514 → 578
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:703 → 852
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    12. XM_024449060.2 → XP_024304828.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

      Conserved Domains (3) summary
      cd09499
      Location:391 → 457
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:462 → 526
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:651 → 800
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    13. XM_047429166.1 → XP_047285122.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

    14. XM_047429167.1 → XP_047285123.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

      Related
      ENSP00000448512.1, ENST00000547010.5

    15. XM_024449065.2 → XP_024304833.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X15

      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09499
      Location:6 → 72
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:77 → 141
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:266 → 415
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain

    16. XM_047429169.1 → XP_047285125.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X17

      UniProtKB/TrEMBL
      H0YI72

    17. XM_024449069.2 → XP_024304837.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X17

      UniProtKB/TrEMBL
      H0YI72
      Conserved Domains (3) summary
      cd09500
      Location:51 → 115
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      cd01274
      Location:240 → 389
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:1 → 46
      SAM_superfamily; SAM (Sterile alpha motif )

    18. XM_047429168.1 → XP_047285124.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X16

    19. XM_047429170.1 → XP_047285126.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X18

      UniProtKB/TrEMBL
      B4DJA1, B7Z9I9

    20. XM_006719510.5 → XP_006719573.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X8

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1046 → 1195
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    21. XM_006719508.5 → XP_006719571.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X5

      Conserved Domains (8) summary
      cd09499
      Location:811 → 877
      SAM_AIDA1AB-like_repeat1; SAM domain of AIDA1AB-like proteins, repeat 1
      cd09500
      Location:882 → 946
      SAM_AIDA1AB-like_repeat2; SAM domain of AIDA1AB-like proteins, repeat 2
      smart00454
      Location:808 → 873
      SAM; Sterile alpha motif
      cd00204
      Location:53 → 181
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01274
      Location:1071 → 1220
      PTB_Anks; Ankyrin repeat and sterile alpha motif (SAM) domain-containing (Anks) protein family Phosphotyrosine-binding (PTB) domain
      pfam12796
      Location:63 → 158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:7 → 79
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:58 → 89
      ANK; ANK repeat [structural motif]

    22. XM_047429164.1 → XP_047285120.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X12

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      98707730..99946157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054372583.1 → XP_054228558.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X11

    2. XM_054372576.1 → XP_054228551.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X4

    3. XM_054372578.1 → XP_054228553.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X6

    4. XM_054372575.1 → XP_054228550.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X3

    5. XM_054372582.1 → XP_054228557.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X10

    6. XM_054372581.1 → XP_054228556.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X9

    7. XM_054372579.1 → XP_054228554.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X7

    8. XM_054372573.1 → XP_054228548.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X1

    9. XM_054372574.1 → XP_054228549.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X2

    10. XM_054372587.1 → XP_054228562.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

    11. XM_054372586.1 → XP_054228561.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X14

    12. XM_054372585.1 → XP_054228560.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

    13. XM_054372588.1 → XP_054228563.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

    14. XM_054372589.1 → XP_054228564.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X13

    15. XM_054372590.1 → XP_054228565.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X15

      UniProtKB/TrEMBL
      H0YI72

    16. XM_054372592.1 → XP_054228567.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X17

      UniProtKB/TrEMBL
      H0YI72

    17. XM_054372591.1 → XP_054228566.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X16

    18. XM_054372593.1 → XP_054228568.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X18

      UniProtKB/TrEMBL
      B4DJA1, B7Z9I9

    19. XM_054372580.1 → XP_054228555.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X8

    20. XM_054372577.1 → XP_054228552.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X5

    21. XM_054372584.1 → XP_054228559.1  ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X12

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7Z6G8.2 GenPept UniProtKB/Swiss-Prot:Q7Z6G8

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