U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    Rok Rho kinase [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 663533, updated on 10-May-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    Rok
    Gene description
    Rho kinase
    Locus tag
    TcasGA2_TC014705
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Orthologs
    fruit fly all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Rok in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 5 NC_087398.1 (2124381..2131119, complement)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG5 NC_007420.3 (13643237..13649960)

    Chromosome 5 - NC_087398.1Genomic Context describing neighboring genes Neighboring gene tetraspanin-7 Neighboring gene transfer RNA leucine (anticodon CAA) Neighboring gene villin like protein quail Neighboring gene growth hormone-inducible transmembrane protein Neighboring gene ATP-dependent RNA helicase DHX33 Neighboring gene Schwannomin interacting protein 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables Rho-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actomyosin structure organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cortical actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryonic morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell junction assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    rho-associated protein kinase 1
    Names
    AUGUSTUS-3.0.2_14705
    Rho-associated protein kinase 1-like Protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087398.1 Reference icTriCast1.1 Primary Assembly

      Range
      2124381..2131119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015980195.2 → XP_015835681.1  rho-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A139WHG7
      Conserved Domains (7) summary
      smart00109
      Location:1236 → 1282
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00220
      Location:78 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG0419
      Location:568 → 1108
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01242
      Location:1122 → 1231
      PH_ROCK; Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain
      cd05596
      Location:52 → 401
      STKc_ROCK; Catalytic domain of the Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase
      pfam08912
      Location:950 → 1013
      Rho_Binding; Rho Binding
      pfam14662
      Location:445 → 635
      KASH_CCD; Coiled-coil region of CCDC155 or KASH

    2. XM_008196136.3 → XP_008194358.1  rho-associated protein kinase 1 isoform X2

      See identical proteins and their annotated locations for XP_008194358.1

      UniProtKB/TrEMBL
      A0A139WHG7, D6WNY9
      Conserved Domains (7) summary
      smart00109
      Location:1228 → 1274
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00220
      Location:78 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd01242
      Location:1114 → 1223
      PH_ROCK; Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain
      cd05596
      Location:52 → 401
      STKc_ROCK; Catalytic domain of the Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase
      TIGR02168
      Location:517 → 1100
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam08912
      Location:942 → 1005
      Rho_Binding; Rho Binding
      pfam14662
      Location:445 → 635
      KASH_CCD; Coiled-coil region of CCDC155 or KASH

    3. XM_015980197.2 → XP_015835683.1  rho-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A139WHG7
      Conserved Domains (7) summary
      smart00109
      Location:1236 → 1282
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00220
      Location:78 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG0419
      Location:568 → 1108
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01242
      Location:1122 → 1231
      PH_ROCK; Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain
      cd05596
      Location:52 → 401
      STKc_ROCK; Catalytic domain of the Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase
      pfam08912
      Location:950 → 1013
      Rho_Binding; Rho Binding
      pfam14662
      Location:445 → 635
      KASH_CCD; Coiled-coil region of CCDC155 or KASH

    4. XM_015980196.2 → XP_015835682.1  rho-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A139WHG7
      Conserved Domains (7) summary
      smart00109
      Location:1236 → 1282
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00220
      Location:78 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG0419
      Location:568 → 1108
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01242
      Location:1122 → 1231
      PH_ROCK; Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain
      cd05596
      Location:52 → 401
      STKc_ROCK; Catalytic domain of the Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase
      pfam08912
      Location:950 → 1013
      Rho_Binding; Rho Binding
      pfam14662
      Location:445 → 635
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials