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    cpxA envelope stress sensor histidine kinase CpxA [ Klebsiella michiganensis ]

    Gene ID: 66562463, updated on 28-Nov-2024

    Summary

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    Gene symbol
    cpxA
    Gene description
    envelope stress sensor histidine kinase CpxA
    Locus tag
    JLG71_RS27005
    Gene type
    protein coding
    Organism
    Klebsiella michiganensis (strain: THO-011, nat-host: Homo sapiens)
    Lineage
    Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella
    Old locus tag
    THOKLE011_52560
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    Genomic context

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    NZ_AP022547.1Genomic Context describing neighboring genes Neighboring gene CDF family cation-efflux transporter FieF Neighboring gene cell-envelope stress modulator CpxP Neighboring gene envelope stress response regulator transcription factor CpxR Neighboring gene 6-hydroxyaminopurine reductase Neighboring gene superoxide dismutase [Mn]

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_AP022547.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Cpx envelope stress response affects expression of the type IV bundle-forming pili of enteropathogenic Escherichia coli. Nevesinjac AZ, et al. J Bacteriol, 2005 Jan. PMID 15629938, Free PMC Article
    2. The cpx proteins of Escherichia coli K12. Structure of the cpxA polypeptide as an inner membrane component. Weber RF, et al. J Mol Biol, 1988 Sep 20. PMID 3058985
    3. Negative regulation of DNA repair gene (ung) expression by the CpxR/CpxA two-component system in Escherichia coli K-12 and induction of mutations by increased expression of CpxR. Ogasawara H, et al. J Bacteriol, 2004 Dec. PMID 15576781, Free PMC Article
    4. A genomic epidemiological study shows that prevalence of antimicrobial resistance in Enterobacterales is associated with the livestock host, as well as antimicrobial usage. AbuOun M, et al. Microb Genom, 2021 Oct. PMID 34609275, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    envelope stress sensor histidine kinase CpxA
    WP_004107505.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_AP022547.1 Reference assembly

      Range
      5775968..5777341
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_004107505.1 MULTISPECIES: envelope stress sensor histidine kinase CpxA [Klebsiella]

      See identical proteins and their annotated locations for WP_004107505.1

      UniProtKB/TrEMBL
      A0A0E0WUA4, A0A0G3PU41, A0A0H3H495, A0A285AVR5, A0A9Q6U1R5, A0A9Q9UIJ7, A0AAD0Y5R1, A0AAN3RT70, H3N587, J6HPT9
      Conserved Domains (1) summary
      PRK09470
      Location:1 → 456
      cpxA; envelope stress sensor histidine kinase CpxA
    Nucleotide Protein
    Heading Accession and Version