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    DHX8 DEAH-box helicase 8 [ Cebus imitator (Panamanian white-faced capuchin) ]

    Gene ID: 108294300, updated on 14-Mar-2024

    Summary

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    Gene symbol
    DHX8
    Gene description
    DEAH-box helicase 8
    See related
    Ensembl:ENSCCAG00000021748
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cebus imitator
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Cebinae; Cebus
    Orthologs
    human mouse all
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    Genomic context

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    See DHX8 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    101 current Cebus_imitator-1.0 (GCF_001604975.1) Unplaced Scaffold NW_016107888.1 (109131..148964)

    NW_016107888.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene ETS variant transcription factor 4 Neighboring gene uncharacterized LOC108294279

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_016107888 Unplaced Scaffold Reference Cebus_imitator-1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in spliceosomal complex disassembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase DHX8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cebus imitator Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cebus_imitator-1.0

    Genomic

    1. NW_016107888.1 Reference Cebus_imitator-1.0

      Range
      109131..148964
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017516120.2 → XP_017371609.1  ATP-dependent RNA helicase DHX8 isoform X4

      UniProtKB/TrEMBL
      A0A2K5PWV1
      Conserved Domains (4) summary
      COG0539
      Location:259 → 418
      RpsA; Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]
      COG1643
      Location:553 → 1135
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd05684
      Location:261 → 339
      S1_DHX8_helicase; The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced mRNA by releasing ...
      cd21691
      Location:25 → 92
      GH2-like_DHX8; GIPC-homology 2 (GH2)-like domain found in DEAH box protein 8 (DHX8) and similar proteins

    2. XM_017516121.2 → XP_017371610.1  ATP-dependent RNA helicase DHX8 isoform X5

      UniProtKB/TrEMBL
      A0A2K5PWV1
      Conserved Domains (4) summary
      COG0539
      Location:257 → 416
      RpsA; Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]
      COG1643
      Location:551 → 1133
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd05684
      Location:259 → 337
      S1_DHX8_helicase; The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced mRNA by releasing ...
      cd21691
      Location:25 → 92
      GH2-like_DHX8; GIPC-homology 2 (GH2)-like domain found in DEAH box protein 8 (DHX8) and similar proteins

    3. XM_017516119.2 → XP_017371608.1  ATP-dependent RNA helicase DHX8 isoform X3

      UniProtKB/TrEMBL
      A0A2K5PWV1
      Conserved Domains (4) summary
      COG0539
      Location:259 → 418
      RpsA; Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]
      COG1643
      Location:553 → 1163
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd05684
      Location:261 → 339
      S1_DHX8_helicase; The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced mRNA by releasing ...
      cd21691
      Location:25 → 92
      GH2-like_DHX8; GIPC-homology 2 (GH2)-like domain found in DEAH box protein 8 (DHX8) and similar proteins

    4. XM_017516118.2 → XP_017371607.1  ATP-dependent RNA helicase DHX8 isoform X2

      UniProtKB/TrEMBL
      A0A2K5PWV1
      Related
      ENSCCAP00000008071.1, ENSCCAT00000025447.1
      Conserved Domains (4) summary
      COG0539
      Location:257 → 416
      RpsA; Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]
      COG1643
      Location:551 → 1213
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd05684
      Location:259 → 337
      S1_DHX8_helicase; The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced mRNA by releasing ...
      cd21691
      Location:25 → 92
      GH2-like_DHX8; GIPC-homology 2 (GH2)-like domain found in DEAH box protein 8 (DHX8) and similar proteins

    5. XM_017516117.2 → XP_017371606.1  ATP-dependent RNA helicase DHX8 isoform X1

      UniProtKB/TrEMBL
      A0A2K5PWS6, A0A2K5PWV1
      Related
      ENSCCAP00000008046.1, ENSCCAT00000025422.1
      Conserved Domains (4) summary
      COG0539
      Location:259 → 418
      RpsA; Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]
      COG1643
      Location:553 → 1215
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd05684
      Location:261 → 339
      S1_DHX8_helicase; The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced mRNA by releasing ...
      cd21691
      Location:25 → 92
      GH2-like_DHX8; GIPC-homology 2 (GH2)-like domain found in DEAH box protein 8 (DHX8) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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