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    grb7.S growth factor receptor bound protein 7 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 108702490, updated on 27-Dec-2024

    Summary

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    Official Symbol
    grb7.S
    Official Full Name
    growth factor receptor bound protein 7 S homeolog
    Primary source
    Xenbase:XB-GENE-6487443
    Locus tag
    XELAEV_18045922mg
    See related
    EnsemblRapid:ENSXLAG00005028345 AllianceGenome:Xenbase:XB-GENE-6487443
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Summary
    Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in esophagus adenocarcinoma. Orthologous to human GRB7 (growth factor receptor bound protein 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See grb7.S in Genome Data Viewer
    Location:
    chromosome: 9_10S
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (1916905..1944860, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (1833324..1861958, complement)

    Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein Aiolos-like Neighboring gene retinol dehydrogenase 8-like Neighboring gene migration and invasion enhancer 1 S homeolog Neighboring gene nuclear factor 7, brain-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    growth factor receptor-bound protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      1916905..1944860 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018237974.2 → XP_018093463.1  growth factor receptor-bound protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8J0TZY6

    2. XM_041579271.1 → XP_041435205.1  growth factor receptor-bound protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8J1M2E7
      Related
      ENSXLAP00005084664.1, ENSXLAT00005086318.1
      Conserved Domains (3) summary
      cd10413
      Location:509 → 616
      SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
      cd01259
      Location:310 → 432
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      cd16140
      Location:185 → 272
      RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7

    3. XM_018237973.2 → XP_018093462.1  growth factor receptor-bound protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A1L8EKL3, A0A974BS83
      Related
      ENSXLAP00005084748.1, ENSXLAT00005086408.1
    Nucleotide Protein Strain
    Heading Accession and Version

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