slc22a8.S solute carrier family 22 (organic anion transporter), member 8 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: slc22a8.S
Official Full Name: solute carrier family 22 (organic anion transporter), member 8 S homeolog
Primary source: Xenbase:XB-GENE-22061136
Locus tag: XELAEV_18024271mg
See related: EnsemblRapid:ENSXLAG00005010250 AllianceGenome:Xenbase:XB-GENE-22061136
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: oat1-A; slc22a6-A
Summary: Predicted to enable transmembrane transporter activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in basal plasma membrane. Orthologous to human SLC22A8 (solute carrier family 22 member 8). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: chromosome: 4S

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4S	NC_054378.1 (3327885..3362818)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4S	NC_030731.1 (3196826..3231957)

Chromosome 4S - NC_054378.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in basal plasma membrane	IEA Inferred from Electronic Annotation more info
located_in basal plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: solute carrier family 22 member 6-A

Names: ROAT1-A; organic cation transporter 1-A; renal organic anion transporter 1-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094192.1 → NP_001087661.1 solute carrier family 22 member 6-A

See identical proteins and their annotated locations for NP_001087661.1

Status: PROVISIONAL

Source sequence(s)

BC081055

UniProtKB/Swiss-Prot

Q66J54

Related

ENSXLAP00005030199.1, ENSXLAT00005030956.1

Conserved Domains (2) summary

cd06174
Location:140 → 510

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

TIGR00898
Location:11 → 520

2A0119; cation transport protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

3327885..3362818

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041591363.1 → XP_041447297.1 solute carrier family 22 member 6-A isoform X1

UniProtKB/TrEMBL

A0A1L8GD38, A0A974CYK5

Conserved Domains (1) summary

cd17446
Location:105 → 510

MFS_SLC22A6_OAT1_like; Solute carrier family 22 member 6 (also called Organic anion transporter 1) and similar transporters of the Major Facilitator Superfamily