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    ABCB3 P-glycoprotein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826951, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCB3
    Official Full Name
    P-glycoprotein 3
    Primary source
    TAIR:AT4G01820
    Locus tag
    AT4G01820
    See related
    Araport:AT4G01820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATP-binding cassette B3; MDR3; P-glycoprotein 3; PGP3; T7B11.8; T7B11_8
    Summary
    member of MDR subfamily
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    Genomic context

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    See ABCB3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (780646..785340, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein Neighboring gene Albino or Glassy Yellow 1 Neighboring gene Sec23/Sec24 protein transport family protein Neighboring gene P-glycoprotein 5 Neighboring gene Ca2+ activated outward rectifying K+ channel 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis thaliana ABC protein superfamily, a complete inventory. Sánchez-Fernández R, et al. J Biol Chem, 2001 Aug 10. PMID 11346655
    2. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    P-glycoprotein 3
    NP_192091.1
    • P-glycoprotein 3 (PGP3); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: integral to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 5 (TAIR:AT4G01830.1); Has 830190 Blast hits to 386538 proteins in 4151 species: Archae - 14649; Bacteria - 648558; Metazoa - 17709; Fungi - 12207; Plants - 9512; Viruses - 34; Other Eukaryotes - 127521 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      780646..785340 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116412.2 → NP_192091.1  P-glycoprotein 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49749, Q9SYI2
      UniProtKB/TrEMBL
      A0A654FKZ6
      Conserved Domains (3) summary
      cd03249
      Location:348 → 586
      ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
      PTZ00265
      Location:4 → 1223
      PTZ00265; multidrug resistance protein (mdr1); Provisional
      pfam00664
      Location:30 → 286
      ABC_membrane; ABC transporter transmembrane region

    2. NM_001340338.1 → NP_001328373.1  P-glycoprotein 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B4H4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SYI2.1

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