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    galnt11.S polypeptide N-acetylgalactosaminyltransferase 11 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 447314, updated on 20-Nov-2024

    Summary

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    Official Symbol
    galnt11.S
    Official Full Name
    polypeptide N-acetylgalactosaminyltransferase 11 S homeolog
    Primary source
    Xenbase:XB-GENE-981834
    Locus tag
    XELAEV_18032816mg
    See related
    EnsemblRapid:ENSXLAG00005034780 AllianceGenome:Xenbase:XB-GENE-981834
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    galnt11; galnac-t11
    Summary
    Predicted to enable Notch binding activity; carbohydrate binding activity; and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to act upstream of or within protein O-linked glycosylation and regulation of Notch signaling pathway. Predicted to be located in Golgi membrane. Is expressed in urinary system. Orthologous to human GALNT11 (polypeptide N-acetylgalactosaminyltransferase 11). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See galnt11.S in Genome Data Viewer
    Location:
    chromosome: 6S
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6S NC_054382.1 (9005560..9024142)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6S NC_030735.1 (8616004..8634567)

    Chromosome 6S - NC_054382.1Genomic Context describing neighboring genes Neighboring gene Ras homolog, mTORC1 binding S homeolog Neighboring gene protein kinase, AMP-activated, gamma 2 non-catalytic subunit S homeolog Neighboring gene lysine methyltransferase 2C S homeolog Neighboring gene DNA repair protein XRCC2-like S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC81846

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    polypeptide N-acetylgalactosaminyltransferase 11 S homeolog
    Names
    :polypeptide N-acetylgalactosaminyltransferase 11
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
    pp-gantase 11
    NP_001087490.1
    XP_018124221.1
    XP_018124222.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001094021.1 → NP_001087490.1  polypeptide N-acetylgalactosaminyltransferase 11 S homeolog

      See identical proteins and their annotated locations for NP_001087490.1

      Status: PROVISIONAL

      Source sequence(s)
      BC080006
      UniProtKB/TrEMBL
      A0A974CMM1, Q68F39
      Related
      ENSXLAP00005103957.1, ENSXLAT00005105976.1
      Conserved Domains (4) summary
      cd02510
      Location:149 → 447
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      COG0463
      Location:144 → 441
      WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
      cd00161
      Location:484 → 601
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:478 → 599
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      9005560..9024142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018268732.2 → XP_018124221.1  polypeptide N-acetylgalactosaminyltransferase 11 S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A1L8FQI6, A0A974CIB9, A0A974CMM1
      Related
      ENSXLAP00005104154.1, ENSXLAT00005106173.1

    2. XM_018268733.2 → XP_018124222.1  polypeptide N-acetylgalactosaminyltransferase 11 S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A1L8FQI6, A0A974CIB9, A0A974CMM1
      Related
      ENSXLAP00005104183.1, ENSXLAT00005106202.1
    Nucleotide Protein Strain
    Heading Accession and Version

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