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    CKM creatine kinase, M-type [ Bos taurus (domestic cattle) ]

    Gene ID: 286822, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CKMprovided by VGNC
    Official Full Name
    creatine kinase, M-typeprovided by VGNC
    Primary source
    VGNC:VGNC:27385
    See related
    BGD:BT11154; Ensembl:ENSBTAG00000013921
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    CPK-M
    Orthologs
    human mouse all
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    Genomic context

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    See CKM in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (52956486..52965891, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene exocyst complex component 3 like 2 Neighboring gene microtubule affinity regulating kinase 4 Neighboring gene U6 spliceosomal RNA Neighboring gene kinesin light chain 3 Neighboring gene ERCC excision repair 2, TFIIH core complex helicase subunit Neighboring gene protein phosphatase 1 regulatory subunit 13 like Neighboring gene RNA polymerase I subunit G

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. The three-dimensional structure of cytosolic bovine retinal creatine kinase. Tisi D, et al. Acta Crystallogr D Biol Crystallogr, 2001 Feb. PMID 11173463
    2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables creatine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphocreatine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    creatine kinase M-type
    Names
    M-CK
    creatine kinase M chain
    creatine kinase, muscle
    creatine phosphokinase M-type
    muscle creatine kinase
    NP_777198.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174773.4 → NP_777198.2  creatine kinase M-type

      See identical proteins and their annotated locations for NP_777198.2

      Status: PROVISIONAL

      Source sequence(s)
      BC102907
      UniProtKB/Swiss-Prot
      Q5E9Y4, Q9XSC6
      UniProtKB/TrEMBL
      A0A3Q1LX97
      Related
      ENSBTAP00000018492.2, ENSBTAT00000018492.4
      Conserved Domains (1) summary
      cd00716
      Location:16 → 373
      creatine_kinase_like; Phosphagen (guanidino) kinases such as creatine kinase and similar enzymes

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      52956486..52965891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XSC6.2 GenPept UniProtKB/Swiss-Prot:Q9XSC6

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