CA2 carbonic anhydrase 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: CA2provided by CGNC
Full Name: carbonic anhydrase 2provided by CGNC
Primary source: CGNC:11834
See related: Ensembl:ENSGALG00010013325
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

Location:: chromosome: 2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (122451344..122467708)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (122642979..122659356)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Effects in broiler hens of genetic lines differing in fertility, biotin supplementation, and age on relative abundance of oviductal transforming growth factor-beta and carbonic anhydrase mRNA transcripts.
Title: Effects in broiler hens of genetic lines differing in fertility, biotin supplementation, and age on relative abundance of oviductal transforming growth factor-β and carbonic anhydrase mRNA transcripts.
Developmental changes and sexual differences of CA-II concentration in WL-chicken erythrocytes were observed
Title: Biochemical and developmental characterization of carbonic anhydrase II from chicken erythrocytes.

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General gene information

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Markers

CA2sts2 (e-PCR), detects polymorphism
- UniSTS:279814

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables carbonate dehydratase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: carbonic anhydrase 2

Names: CA-II; carbonate dehydratase II; carbonic anhydrase II; cyanamide hydratase CA2

NP_990648.1

EC 4.2.1.1

EC 4.2.1.69

XP_040532604.1

EC 4.2.1.1

EC 4.2.1.69

XP_046766411.1

EC 4.2.1.1

EC 4.2.1.69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205317.2 → NP_990648.1 carbonic anhydrase 2

See identical proteins and their annotated locations for NP_990648.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000044

UniProtKB/Swiss-Prot

P07630

UniProtKB/TrEMBL

A0A8V0YLT1

Related

ENSGALP00010018863.1, ENSGALT00010032073.1

Conserved Domains (1) summary

cd03119
Location:1 → 259

alpha_CA_I_II_III_XIII; Carbonic anhydrase alpha, isozymes I, II, and III and XIII. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

122451344..122467708

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040676670.2 → XP_040532604.1 carbonic anhydrase 2 isoform X1

Conserved Domains (1) summary

cl00012
Location:1 → 182

alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...