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    LIMA1 LIM domain and actin binding 1 [ Sus scrofa (pig) ]

    Gene ID: 100137084, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LIMA1provided by VGNC
    Official Full Name
    LIM domain and actin binding 1provided by VGNC
    Primary source
    VGNC:VGNC:98070
    See related
    Ensembl:ENSSSCG00000032269
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    EPLIN
    Expression
    Ubiquitous expression in kidney (RPKM 22.1), subcutaneous adipose (RPKM 14.4) and 8 other tissues See more
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See LIMA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (16074436..16177122, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (16487730..16492647, complement)

    Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase assembly protein COX14 Neighboring gene glycerol-3-phosphate dehydrogenase 1 Neighboring gene ceramide synthase 5 Neighboring gene La ribonucleoprotein 4 Neighboring gene family with sequence similarity 186 member A Neighboring gene disco interacting protein 2 homolog B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Characterization of porcine EPLIN gene revealed distinct expression patterns for the two isoforms. Wang H, et al. Anim Biotechnol, 2007. PMID 17453649
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LIM domain and actin-binding protein 1
    Names
    EPLIN-b
    epithelial protein lost in neoplasm

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114676.1 → NP_001108148.1  LIM domain and actin-binding protein 1

      See identical proteins and their annotated locations for NP_001108148.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ364062
      UniProtKB/Swiss-Prot
      B0KYV5, B0KYV6
      UniProtKB/TrEMBL
      A0A8D1B8R9, A0A8D1R9H9
      Related
      ENSSSCP00000038082.2, ENSSSCT00000048726.3
      Conserved Domains (1) summary
      cd09485
      Location:386 → 438
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

      Range
      16074436..16177122 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021090879.1 → XP_020946538.1  LIM domain and actin-binding protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A5G2QDK2, A0A8D1KS08
      Related
      ENSSSCP00000060135.1, ENSSSCT00000085569.1
      Conserved Domains (1) summary
      cd09485
      Location:362 → 414
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    2. XM_021090876.1 → XP_020946535.1  LIM domain and actin-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8D1KS08
      Conserved Domains (1) summary
      cd09485
      Location:371 → 423
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    3. XM_021090873.1 → XP_020946532.1  LIM domain and actin-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8D1GPB3
      Conserved Domains (1) summary
      cd09485
      Location:395 → 447
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    4. XM_021090869.1 → XP_020946528.1  LIM domain and actin-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A287AGB6, A0A8D1GPB3
      Conserved Domains (1) summary
      cd09485
      Location:396 → 448
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    5. XM_021090877.1 → XP_020946536.1  LIM domain and actin-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8D1KS08
      Conserved Domains (1) summary
      cd09485
      Location:371 → 423
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    6. XM_021090870.1 → XP_020946529.1  LIM domain and actin-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A287AGB6, A0A8D1GPB3
      Related
      ENSSSCP00000042877.2, ENSSSCT00000051991.3
      Conserved Domains (1) summary
      cd09485
      Location:396 → 448
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    7. XM_021090871.1 → XP_020946530.1  LIM domain and actin-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A287AGB6, A0A8D1GPB3
      Conserved Domains (1) summary
      cd09485
      Location:396 → 448
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    8. XM_021090878.1 → XP_020946537.1  LIM domain and actin-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8D1KS08
      Conserved Domains (1) summary
      cd09485
      Location:371 → 423
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    9. XM_021090874.1 → XP_020946533.1  LIM domain and actin-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A287A2U9
      Conserved Domains (1) summary
      cd09485
      Location:387 → 439
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)

    10. XM_021090875.1 → XP_020946534.1  LIM domain and actin-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A287A2U9
      Conserved Domains (1) summary
      cd09485
      Location:387 → 439
      LIM_Eplin_alpha_beta; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B0KYV5.1 GenPept UniProtKB/Swiss-Prot:B0KYV5

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