U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    CG12744 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36024, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG12744provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033459
    Locus tag
    Dmel_CG12744
    See related
    AllianceGenome:FB:FBgn0033459
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12744
    Summary
    Involved in defense response to fungus. Is expressed in embryonic/larval salivary gland; gonad; head mesoderm; organism; and trunk mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG12744 in Genome Data Viewer
    Location:
    46C1-46C1; 2-61 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9874889..9876242)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5762786..5763747)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45138 Neighboring gene pendolino Neighboring gene Linking immunity and metabolism Neighboring gene Secretory 24AB Neighboring gene antisense RNA:CR45467 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The zinc finger protein CG12744 is essential for differentiation and regeneration after infection in the adult Drosophila midgut. Liu Q, et al. Exp Cell Res, 2017 Dec 15. PMID 29074370
    2. The zinc finger protein CG12744 regulates intestinal stem cells in aged Drosophila through the EGFR and BMP pathways. Wang J, et al. Life Sci, 2024 Mar 1. PMID 38311220
    3. Identification of genes involved in the same pathways using a Hidden Markov Model-based approach. Senf A, et al. Bioinformatics, 2009 Nov 15. PMID 19720676
    4. Identification and functional analysis of antifungal immune response genes in Drosophila. Jin LH, et al. PLoS Pathog, 2008 Oct 3. PMID 18833296, Free PMC Article
    5. New Drosophila Long-Term Memory Genes Revealed by Assessing Computational Function Prediction Methods. Kacsoh BZ, et al. G3 (Bethesda), 2019 Jan 9. PMID 30463884, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The zinc finger protein CG12744 regulates intestinal stem cells in aged Drosophila through the EGFR and BMP pathways.
      Title: The zinc finger protein CG12744 regulates intestinal stem cells in aged Drosophila through the EGFR and BMP pathways.
    2. CG12744 maintained epithelial architecture and cell fate in enterocytes following an acute infectious challenge.
      Title: The zinc finger protein CG12744 is essential for differentiation and regeneration after infection in the adult Drosophila midgut.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG12744-PA
    CG12744-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9874889..9876242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136686.5 → NP_610530.1  uncharacterized protein Dmel_CG12744, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610530.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JUR5
      UniProtKB/TrEMBL
      E2QC93
      Related
      FBpp0087466
      Conserved Domains (1) summary
      sd00017
      Location:12 → 32
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_165717.3 → NP_724850.1  uncharacterized protein Dmel_CG12744, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724850.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JUR5
      UniProtKB/TrEMBL
      E2QC93
      Related
      FBpp0087465
      Conserved Domains (1) summary
      sd00017
      Location:12 → 32
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E2QC93 E2QC93
    Q7JUR5.1 Q7JUR5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools