Eif3j1 eukaryotic translation initiation factor 3, subunit J1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Eif3j1provided by MGI
Official Full Name: eukaryotic translation initiation factor 3, subunit J1provided by MGI
Primary source: MGI:MGI:1925905
See related: Ensembl:ENSMUSG00000027236 AllianceGenome:MGI:1925905
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Eif3j; Eif3j2; Eif3s1; Eif3j-1; Eif3j-2; eIF3j-A; eIF3j-B; eIF3-p35; eIF3-alpha; 1810016I04Rik; 2700079K05Rik; eIF-3-alpha-A; eIF-3-alpha-B
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in formation of cytoplasmic translation initiation complex. Predicted to be located in cytosol. Predicted to be part of eukaryotic translation initiation factor 3 complex. Orthologous to human EIF3J (eukaryotic translation initiation factor 3 subunit J). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in CNS E11.5 (RPKM 29.5), liver E14 (RPKM 27.9) and 26 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2 E5; 2 60.49 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (121859061..121884113)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (122028580..122053632)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

eIF-3-alpha interferes with Ras-induced focus formation in NIH 3T3 cells.
Title: Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH126537 (e-PCR)
- UniSTS:207391

RH126395 (e-PCR)
- UniSTS:163103

RH124823 (e-PCR)
- UniSTS:161645

RH124861 (e-PCR)
- UniSTS:161683

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in formation of cytoplasmic translation initiation complex	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info
part_of eukaryotic 43S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic 48S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 3 complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 3 subunit J

Names: eukaryotic translation initiation factor 3 subunit 1-A; eukaryotic translation initiation factor 3 subunit 1-B; eukaryotic translation initiation factor 3, subunit 1 alpha; eukaryotic translation initiation factor 3, subunit J

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.