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    iscS cysteine desulfurase [ Enterobacter cloacae ]

    Gene ID: 83574720, updated on 3-Dec-2024

    Summary

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    Gene symbol
    iscS
    Gene description
    cysteine desulfurase
    Locus tag
    LQ108_RS17045
    Gene type
    protein coding
    Organism
    Enterobacter cloacae (isolate: 1382, nat-host: Homo sapiens)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex
    Old locus tag
    AI2999V1_3322
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    Genomic context

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    Location:
    chromosome: main

    main - NZ_OW968328.1Genomic Context describing neighboring genes Neighboring gene iron-sulfur cluster assembly protein IscA Neighboring gene Fe-S cluster assembly scaffold IscU Neighboring gene Fe-S cluster assembly transcriptional regulator IscR Neighboring gene tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_OW968328.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel Carbapenemases FLC-1 and IMI-2 Encoded by an Enterobacter cloacae Complex Isolated from Food Products. Brouwer MSM, et al. Antimicrob Agents Chemother, 2019 Jun. PMID 30910900, Free PMC Article
    2. Disordered form of the scaffold protein IscU is the substrate for iron-sulfur cluster assembly on cysteine desulfurase. Kim JH, et al. Proc Natl Acad Sci U S A, 2012 Jan 10. PMID 22203963, Free PMC Article
    3. Crystal structure of IscS, a cysteine desulfurase from Escherichia coli. Cupp-Vickery JR, et al. J Mol Biol, 2003 Jul 25. PMID 12860127
    4. The cysteine desulfurase, IscS, has a major role in in vivo Fe-S cluster formation in Escherichia coli. Schwartz CJ, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10908675, Free PMC Article
    5. Transfer of sulfur from IscS to IscU during Fe/S cluster assembly. Urbina HD, et al. J Biol Chem, 2001 Nov 30. PMID 11577100

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    cysteine desulfurase
    WP_003860663.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_OW968328.1 Reference assembly

      Range
      3598776..3599990 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_003860663.1 MULTISPECIES: cysteine desulfurase [Enterobacter]

      See identical proteins and their annotated locations for WP_003860663.1

      UniProtKB/TrEMBL
      A0A094WXR5, A0A0F1BD05, A0A0H3CNC4, A0A0M7GHH3, A0A167IGH9, A0A2J7SUS3, A0A329HZS0, A0A330DVA8, A0A331VV21, A0A428LIA1, A0A4Q2R2Y6, A0A851G7K5, A0A8B3JSY5, A0A8E1RQJ0, A0A9W3Q3Y8, A0AA37AJF3, A0AA96RSQ5, A0AAE2EEQ0, A0AAE4J497, A0AAE8QY07, A0AAN1H4P5, A0AAU6NGS0, A0AAU7N9A8, A0AAV3KUC5
    Nucleotide Protein
    Heading Accession and Version