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    NCK2 NCK adaptor protein 2 [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

    Gene ID: 111542152, updated on 15-Mar-2024

    Summary

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    Gene symbol
    NCK2
    Gene description
    NCK adaptor protein 2
    See related
    Ensembl:ENSPTEG00000032149
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Piliocolobus tephrosceles
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
    Orthologs
    human mouse all
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    Genomic context

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    See NCK2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    102 current ASM277652v3 (GCF_002776525.3) 15 NC_045448.1 (98761917..98917949, complement)
    100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019317172.1 (927782..1079233, complement)

    Chromosome 15 - NC_045448.1Genomic Context describing neighboring genes Neighboring gene UDP-glucuronate decarboxylase 1 Neighboring gene ECRG4 augurin precursor Neighboring gene uncharacterized LOC111542156 Neighboring gene chromosome 15 C2orf49 homolog Neighboring gene four and a half LIM domains 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of PERK-mediated unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of translation in response to endoplasmic reticulum stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytoplasmic protein NCK2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM277652v3

    Genomic

    1. NC_045448.1 Reference ASM277652v3

      Range
      98761917..98917949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023211309.2 → XP_023067077.1  cytoplasmic protein NCK2 isoform X3

      Conserved Domains (1) summary
      cd11899
      Location:4 → 61
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein

    2. XM_023211306.2 → XP_023067074.1  cytoplasmic protein NCK2 isoform X1

      UniProtKB/TrEMBL
      A0A8C9ICC6
      Conserved Domains (4) summary
      cd10409
      Location:285 → 382
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:4 → 61
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:116 → 170
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:200 → 258
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    3. XM_023211307.2 → XP_023067075.1  cytoplasmic protein NCK2 isoform X1

      UniProtKB/TrEMBL
      A0A8C9ICC6
      Related
      ENSPTEP00000033738.1
      Conserved Domains (4) summary
      cd10409
      Location:285 → 382
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:4 → 61
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:116 → 170
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:200 → 258
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    4. XM_023211305.2 → XP_023067073.1  cytoplasmic protein NCK2 isoform X1

      UniProtKB/TrEMBL
      A0A8C9ICC6
      Conserved Domains (4) summary
      cd10409
      Location:285 → 382
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11899
      Location:4 → 61
      SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
      cd11902
      Location:116 → 170
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:200 → 258
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein

    5. XM_023211308.1 → XP_023067076.1  cytoplasmic protein NCK2 isoform X2

      Conserved Domains (3) summary
      cd10409
      Location:233 → 330
      SH2_Nck2; Src homology 2 (SH2) domain found in Nck
      cd11902
      Location:64 → 118
      SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
      cd11903
      Location:148 → 206
      SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein
    Nucleotide Protein
    Heading Accession and Version

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