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    Mapk7 mitogen-activated protein kinase 7 [ Mus musculus (house mouse) ]

    Gene ID: 23939, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mapk7provided by MGI
    Official Full Name
    mitogen-activated protein kinase 7provided by MGI
    Primary source
    MGI:MGI:1346347
    See related
    Ensembl:ENSMUSG00000001034 AllianceGenome:MGI:1346347
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BMK1; ERK5; BMK-1; ERK-5; PRKM7; Erk5-T; b2b2346Clo
    Summary
    Enables protein serine/threonine kinase activity. Involved in protein phosphorylation. Acts upstream of or within several processes, including negative regulation of calcineurin-NFAT signaling cascade; peptidyl-serine phosphorylation; and regulation of angiogenesis. Located in cytosol and nucleus. Is expressed in several structures, including cardiovascular system; early conceptus; gonad; nervous system; and salivary gland. Orthologous to human MAPK7 (mitogen-activated protein kinase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 31.7), whole brain E14.5 (RPKM 29.9) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mapk7 in Genome Data Viewer
    Location:
    11 B2; 11 37.96 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (61379638..61385101, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (61488812..61494267, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 112 Neighboring gene STARR-positive B cell enhancer ABC_E6995 Neighboring gene microfibrillar-associated protein 4 Neighboring gene B9 protein domain 1, opposite strand Neighboring gene B9 protein domain 1 Neighboring gene epsin 2 Neighboring gene STARR-seq mESC enhancer starr_29682

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Big mitogen-activated protein kinase 1/extracellular signal-regulated kinase 5 signaling pathway is essential for tumor-associated angiogenesis. Hayashi M, et al. Cancer Res, 2005 Sep 1. PMID 16140937
    2. EGCG Suppresses ERK5 Activation to Reverse Tobacco Smoke-Triggered Gastric Epithelial-Mesenchymal Transition in BALB/c Mice. Lu L, et al. Nutrients, 2016 Jul 20. PMID 27447666, Free PMC Article
    3. ERK5 kinase activity is dispensable for cellular immune response and proliferation. Lin EC, et al. Proc Natl Acad Sci U S A, 2016 Oct 18. PMID 27679845, Free PMC Article
    4. ERK5 is a critical mediator of inflammation-driven cancer. Finegan KG, et al. Cancer Res, 2015 Feb 15. PMID 25649771, Free PMC Article
    5. Role of extracellular signal-regulated kinase 5 in adipocyte signaling. Zhu H, et al. J Biol Chem, 2014 Feb 28. PMID 24425864, Free PMC Article

    See all (152) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1.
      Title: HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1.
    2. Aerobic Exercise Alters the Melanoma Microenvironment and Modulates ERK5 S496 Phosphorylation.
      Title: Aerobic Exercise Alters the Melanoma Microenvironment and Modulates ERK5 S496 Phosphorylation.
    3. An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis.
      Title: An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis.
    4. Polarized macrophages promote gestational beta cell growth through extracellular signal-regulated kinase 5 signalling.
      Title: Polarized macrophages promote gestational beta cell growth through extracellular signal-regulated kinase 5 signalling.
    5. Erk5 in Bone Marrow Mesenchymal Stem Cells Regulates Bone Homeostasis by Preventing Osteogenesis in Adulthood.
      Title: Erk5 in Bone Marrow Mesenchymal Stem Cells Regulates Bone Homeostasis by Preventing Osteogenesis in Adulthood.
    6. ERK5 inhibitor BIX02189 attenuates methamphetamine-induced hyperactivity by modulating microglial activation in the striatum.
      Title: ERK5 inhibitor BIX02189 attenuates methamphetamine-induced hyperactivity by modulating microglial activation in the striatum.
    7. ERK5 negatively regulates Kruppel-like factor 4 and promotes osteogenic lineage cell proliferation in response to MEK5 overexpression or fluid shear stress.
      Title: ERK5 negatively regulates Kruppel-like factor 4 and promotes osteogenic lineage cell proliferation in response to MEK5 overexpression or fluid shear stress.
    8. An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
      Title: An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
    9. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression.
      Title: MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression.
    10. Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner.
      Title: Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner.
    Submit: New GeneRIF Correction See all GeneRIFs (108)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Targeted (7)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables JUN kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables MAP kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables mitogen-activated protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mitogen-activated protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ERK5 cascade ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of calcineurin-NFAT signaling cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular response to hydrogen peroxide IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to hydrogen peroxide ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular response to laminar fluid shear stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to laminar fluid shear stress ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular response to transforming growth factor beta stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to transforming growth factor beta stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within negative regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of calcineurin-NFAT signaling cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of endothelial cell apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of endothelial cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of heterotypic cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of heterotypic cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of response to cytokine stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of response to cytokine stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of smooth muscle cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of smooth muscle cell apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within peptidyl-serine phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of protein metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of protein metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in PML body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in PML body ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 7
    Names
    MAPK 7
    big MAP kinase 1
    extracellular signal-regulated kinase 5
    NP_001277962.1
    NP_001277963.1
    NP_001277964.1
    NP_001277965.1
    NP_001277966.1
    NP_001348918.1
    NP_035971.1
    XP_006533340.1
    XP_006533343.1
    XP_006533347.1
    XP_006533348.1
    XP_006533349.1
    XP_030101845.1
    XP_030101846.1
    XP_030101847.1
    XP_030101848.1
    XP_030101849.1
    XP_030101850.1
    XP_030101851.1
    XP_030101853.1
    XP_036012575.1
    XP_036012576.1
    XP_036012577.1
    XP_036012578.1
    XP_036012579.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291033.1 → NP_001277962.1  mitogen-activated protein kinase 7 isoform b

      See identical proteins and their annotated locations for NP_001277962.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in its 5' UTR uses an alternate start codon, compared to variant 1. The encoded isoform (b) has a shorter and distinct N-terminus, compared to isoform a.
      Source sequence(s)
      AF126160, AY534740, BY207876
      Consensus CDS
      CCDS70205.1
      UniProtKB/Swiss-Prot
      Q9WVS8
      Related
      ENSMUSP00000104354.2, ENSMUST00000108714.2
      Conserved Domains (1) summary
      cd07855
      Location:6 → 315
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    2. NM_001291034.1 → NP_001277963.1  mitogen-activated protein kinase 7 isoform a

      See identical proteins and their annotated locations for NP_001277963.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AY534740, BC100398, BY207876
      Consensus CDS
      CCDS24814.1
      UniProtKB/Swiss-Prot
      Q3U2N7, Q3UG52, Q497T0, Q5NCN6, Q5NCN7, Q5NCN9, Q6QLU8, Q9R1D9, Q9WVF3, Q9WVF4, Q9WVS8
      Conserved Domains (1) summary
      cd07855
      Location:49 → 384
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    3. NM_001291035.1 → NP_001277964.1  mitogen-activated protein kinase 7 isoform c

      See identical proteins and their annotated locations for NP_001277964.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in its 5' UTR uses a downstream start codon, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a. Both variants 4 and 5 encode the same isoform.
      Source sequence(s)
      AY534740, BC082315, BY207876
      UniProtKB/Swiss-Prot
      Q9WVS8
      Related
      ENSMUST00000152755.8
      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    4. NM_001291036.1 → NP_001277965.1  mitogen-activated protein kinase 7 isoform c

      See identical proteins and their annotated locations for NP_001277965.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in its 5' UTR uses a downstream start codon, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a. Both variants 4 and 5 encode the same isoform.
      Source sequence(s)
      AY534740, BY207876, CA320276
      UniProtKB/Swiss-Prot
      Q9WVS8
      Related
      ENSMUST00000125840.8
      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    5. NM_001291037.1 → NP_001277966.1  mitogen-activated protein kinase 7 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in its 5' UTR, uses an alternate start codon, and uses an alternate splice site in the central coding region, compared to variant 1. The encoded isoform (d) is shorter and has a distinct N-terminus, compared to isoform a.
      Source sequence(s)
      AF126161, AY534740, BC058096, BY207876
      Consensus CDS
      CCDS78963.1
      UniProtKB/TrEMBL
      Q5NCN8
      Related
      ENSMUSP00000098646.3, ENSMUST00000101085.9
      Conserved Domains (2) summary
      smart00220
      Location:8 → 277
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd07855
      Location:8 → 314
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    6. NM_001361989.1 → NP_001348918.1  mitogen-activated protein kinase 7 isoform c

      Status: VALIDATED

      Source sequence(s)
      AY534740, BB868535, BC082315, CA315160
      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    7. NM_011841.2 → NP_035971.1  mitogen-activated protein kinase 7 isoform a

      See identical proteins and their annotated locations for NP_035971.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a). Both variants 1 and 2 encode the same isoform.
      Source sequence(s)
      AY534740, BY207876
      Consensus CDS
      CCDS24814.1
      UniProtKB/Swiss-Prot
      Q3U2N7, Q3UG52, Q497T0, Q5NCN6, Q5NCN7, Q5NCN9, Q6QLU8, Q9R1D9, Q9WVF3, Q9WVF4, Q9WVS8
      Related
      ENSMUSP00000078087.7, ENSMUST00000079080.13
      Conserved Domains (1) summary
      cd07855
      Location:49 → 384
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      61379638..61385101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533277.5 → XP_006533340.1  mitogen-activated protein kinase 7 isoform X1

      See identical proteins and their annotated locations for XP_006533340.1

      UniProtKB/Swiss-Prot
      Q3U2N7, Q3UG52, Q497T0, Q5NCN6, Q5NCN7, Q5NCN9, Q6QLU8, Q9R1D9, Q9WVF3, Q9WVF4, Q9WVS8
      Conserved Domains (1) summary
      cd07855
      Location:49 → 384
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    2. XM_030245986.2 → XP_030101846.1  mitogen-activated protein kinase 7 isoform X2

      Conserved Domains (1) summary
      cd07855
      Location:6 → 315
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    3. XM_030245993.2 → XP_030101853.1  mitogen-activated protein kinase 7 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    4. XM_030245989.2 → XP_030101849.1  mitogen-activated protein kinase 7 isoform X3

      Conserved Domains (1) summary
      cd07855
      Location:8 → 314
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    5. XM_006533285.5 → XP_006533348.1  mitogen-activated protein kinase 7 isoform X4

      See identical proteins and their annotated locations for XP_006533348.1

      UniProtKB/Swiss-Prot
      Q9WVS8
      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    6. XM_036156683.1 → XP_036012576.1  mitogen-activated protein kinase 7 isoform X3

      Conserved Domains (1) summary
      cd07855
      Location:8 → 314
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    7. XM_006533284.5 → XP_006533347.1  mitogen-activated protein kinase 7 isoform X4

      See identical proteins and their annotated locations for XP_006533347.1

      UniProtKB/Swiss-Prot
      Q9WVS8
      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    8. XM_030245987.2 → XP_030101847.1  mitogen-activated protein kinase 7 isoform X3

      Conserved Domains (1) summary
      cd07855
      Location:8 → 314
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    9. XM_036156684.1 → XP_036012577.1  mitogen-activated protein kinase 7 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    10. XM_030245988.2 → XP_030101848.1  mitogen-activated protein kinase 7 isoform X3

      Conserved Domains (1) summary
      cd07855
      Location:8 → 314
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    11. XM_006533286.5 → XP_006533349.1  mitogen-activated protein kinase 7 isoform X4

      See identical proteins and their annotated locations for XP_006533349.1

      UniProtKB/Swiss-Prot
      Q9WVS8
      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    12. XM_036156686.1 → XP_036012579.1  mitogen-activated protein kinase 7 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    13. XM_030245985.2 → XP_030101845.1  mitogen-activated protein kinase 7 isoform X2

      Conserved Domains (1) summary
      cd07855
      Location:6 → 315
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    14. XM_036156685.1 → XP_036012578.1  mitogen-activated protein kinase 7 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    15. XM_036156682.1 → XP_036012575.1  mitogen-activated protein kinase 7 isoform X3

      Conserved Domains (1) summary
      cd07855
      Location:8 → 314
      STKc_ERK5; Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5

    16. XM_030245990.2 → XP_030101850.1  mitogen-activated protein kinase 7 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    17. XM_030245991.2 → XP_030101851.1  mitogen-activated protein kinase 7 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain

    18. XM_006533280.5 → XP_006533343.1  mitogen-activated protein kinase 7 isoform X4

      See identical proteins and their annotated locations for XP_006533343.1

      UniProtKB/Swiss-Prot
      Q9WVS8
      Conserved Domains (1) summary
      cl21453
      Location:1 → 245
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9WVS8.1 GenPept UniProtKB/Swiss-Prot:Q9WVS8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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