HNRNPU heterogeneous nuclear ribonucleoprotein U [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: HNRNPUprovided by VGNC
Official Full Name: heterogeneous nuclear ribonucleoprotein Uprovided by VGNC
Primary source: VGNC:VGNC:11451
Locus tag: CK820_G0037045
See related: Ensembl:ENSPTRG00000002182
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: HNRPU
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (4289451..4303495)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (227019820..227031131, complement)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

NoName (e-PCR)
- UniSTS:546820

Hnrnpu (e-PCR), detects polymorphism
- UniSTS:546820

HNRPU (e-PCR)
- UniSTS:506402

GDB:6028664 (e-PCR)
- UniSTS:60734

HNRPU_1518 (e-PCR)
- UniSTS:277316

MARC_12257-12258:1008001094:5 (e-PCR)
- UniSTS:267386

MARC_12257-12258:1044472182:2 (e-PCR)
- UniSTS:267386

RH18125 (e-PCR)
- UniSTS:42376

C86794 (e-PCR)
- UniSTS:207257

RH92446 (e-PCR)
- UniSTS:84894

MARC_20677-20678:1024509130:1 (e-PCR)
- UniSTS:268469

SHGC-76609 (e-PCR)
- UniSTS:36278

D14S1285 (e-PCR)
- UniSTS:10169

A007A33 (e-PCR)
- UniSTS:49593

MARC_26419-26420:1036768776:5 (e-PCR)
- UniSTS:268990

WI-7584 (e-PCR)
- UniSTS:31692

WI-8450 (e-PCR)
- UniSTS:79572

SHGC-76627 (e-PCR)
- UniSTS:3545

SHGC-76621 (e-PCR)
- UniSTS:46824

D1S3027 (e-PCR)
- UniSTS:72191

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables RNA polymerase II C-terminal domain binding	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables TFIIH-class transcription factor complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables poly(C) RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables poly(G) binding	IEA Inferred from Electronic Annotation more info	PubMed
enables pre-mRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables promoter-specific chromatin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ribonucleoprotein complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables snRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription corepressor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in CRD-mediated mRNA stabilization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in RNA localization to chromatin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of telomere maintenance via telomerase	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of attachment of mitotic spindle microtubules to kinetochore	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of chromatin organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of mitotic spindle assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of CRD-mediated mRNA stability complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of catalytic step 2 spliceosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in centrosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasmic ribonucleoprotein granule	IEA Inferred from Electronic Annotation more info	PubMed
located_in inactive sex chromosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in kinetochore	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitotic spindle microtubule	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitotic spindle midzone	IEA Inferred from Electronic Annotation more info	PubMed
located_in nuclear chromosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in nuclear matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in nuclear speck	IEA Inferred from Electronic Annotation more info	PubMed
part_of telomerase holoenzyme complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: heterogeneous nuclear ribonucleoprotein U

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001280278.1 → NP_001267207.1 heterogeneous nuclear ribonucleoprotein U

See identical proteins and their annotated locations for NP_001267207.1

Status: PROVISIONAL

Source sequence(s)

AK306733

UniProtKB/TrEMBL

A0A2J8KNK2, A0A803KKH6, G2HJ19, H2Q1G0

Related

ENSPTRP00000003693.6, ENSPTRT00000004000.6

Conserved Domains (3) summary

smart00513
Location:8 → 42

SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation

cd12884
Location:269 → 444

SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1

pfam13671
Location:480 → 624

AAA_33; AAA domain

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

4289451..4303495

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016922581.4 → XP_016778070.1 heterogeneous nuclear ribonucleoprotein U isoform X1

UniProtKB/TrEMBL

A0A2J8KNK7, A0A6D2VXI7, H2Q1G0, K7CHI6

Related

ENSPTRP00000084872.1

Conserved Domains (3) summary

smart00513
Location:8 → 42

SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation

cd12884
Location:288 → 463

SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1

pfam13671
Location:499 → 643

AAA_33; AAA domain