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    TLX2 T cell leukemia homeobox 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 740883, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TLX2provided by VGNC
    Official Full Name
    T cell leukemia homeobox 2provided by VGNC
    Primary source
    VGNC:VGNC:49086
    Locus tag
    CK820_G0035692
    See related
    Ensembl:ENSPTRG00000012095
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See TLX2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (48231451..48242818, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (74610412..74621779)

    Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene lysyl oxidase like 3 Neighboring gene HtrA serine peptidase 2 Neighboring gene AUP1 lipid droplet regulating VLDL assembly factor Neighboring gene DEAQ-box RNA dependent ATPase 1 Neighboring gene uncharacterized LOC107973524 Neighboring gene polycomb group ring finger 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-cell leukemia homeobox protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      48231451..48242818 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016948844.3 → XP_016804333.1  T-cell leukemia homeobox protein 2

      UniProtKB/TrEMBL
      A0A2J8KV43, A0A6D2WTD2, H2QI68
      Related
      ENSPTRP00000020756.5
      Conserved Domains (1) summary
      pfam00046
      Location:160 → 214
      Homeobox; Homeobox domain

    RNA

    1. XR_008546280.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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