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    TRIM37 tripartite motif containing 37 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 455163, updated on 3-Dec-2024

    Summary

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    Official Symbol
    TRIM37provided by VGNC
    Official Full Name
    tripartite motif containing 37provided by VGNC
    Primary source
    VGNC:VGNC:9740
    Locus tag
    CK820_G0020867
    See related
    Ensembl:ENSPTRG00000009460
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See TRIM37 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (72104123..72228046, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (70288575..70412152, complement)

    Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene RAD51 paralog C Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1E Neighboring gene U6 spliceosomal RNA Neighboring gene U2 spliceosomal RNA Neighboring gene spindle and kinetochore associated complex subunit 2 Neighboring gene microRNA mir-454

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of centriole replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein autoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in aggresome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM37
    Names
    tripartite motif-containing 37 protein
    tripartite motif-containing protein 37
    XP_003315692.1
    XP_009431211.1
    XP_009431212.1
    XP_009431213.2
    XP_009431214.1
    XP_016786318.1
    XP_016786319.1
    XP_016786321.1
    XP_016786322.1
    XP_024206457.1
    XP_024206459.1
    XP_054526476.1
    XP_054526478.1
    XP_054526480.1
    XP_054526482.1
    XP_054526483.1
    XP_054526485.1
    XP_063655111.1
    XP_063655112.1
    XP_063655113.1
    XP_063655114.1
    XP_063655116.1
    XP_063655117.1
    XP_063655118.1
    XP_063655119.1
    XP_063655121.1
    XP_063655122.1
    XP_063655123.1
    XP_063655124.1
    XP_063655125.1
    XP_063655126.1
    XP_063655127.1
    XP_063655128.1
    XP_063655129.1
    XP_063655131.1
    XP_063655132.1
    XP_063655133.1
    XP_063655134.1
    XP_063655135.1
    XP_063655136.1
    XP_063655137.1
    XP_063655138.1
    XP_063655139.1
    XP_063655140.1
    XP_063655141.1
    XP_063655142.1
    XP_063655143.1
    XP_063655144.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      72104123..72228046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063799049.1 → XP_063655119.1  E3 ubiquitin-protein ligase TRIM37 isoform X23

    2. XM_054670507.2 → XP_054526482.1  E3 ubiquitin-protein ligase TRIM37 isoform X22

    3. XM_063799047.1 → XP_063655117.1  E3 ubiquitin-protein ligase TRIM37 isoform X16

    4. XM_063799048.1 → XP_063655118.1  E3 ubiquitin-protein ligase TRIM37 isoform X20

    5. XM_063799071.1 → XP_063655141.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    6. XM_063799072.1 → XP_063655142.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    7. XM_063799068.1 → XP_063655138.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    8. XM_063799069.1 → XP_063655139.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    9. XM_009432939.5 → XP_009431214.1  E3 ubiquitin-protein ligase TRIM37 isoform X21

      See identical proteins and their annotated locations for XP_009431214.1

      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      cd00162
      Location:15 → 58
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      pfam00643
      Location:90 → 132
      zf-B_box; B-box zinc finger

    10. XM_063799044.1 → XP_063655114.1  E3 ubiquitin-protein ligase TRIM37 isoform X14

    11. XM_003315644.6 → XP_003315692.1  E3 ubiquitin-protein ligase TRIM37 isoform X13

      See identical proteins and their annotated locations for XP_003315692.1

      UniProtKB/TrEMBL
      A0A2I3RKX5, A0A2J8MF06, A0A6D2XLE1
      Related
      ENSPTRP00000065016.1
      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91 → 132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    12. XM_063799042.1 → XP_063655112.1  E3 ubiquitin-protein ligase TRIM37 isoform X4

    13. XM_009432936.3 → XP_009431211.1  E3 ubiquitin-protein ligase TRIM37 isoform X11

      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91 → 132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    14. XM_063799041.1 → XP_063655111.1  E3 ubiquitin-protein ligase TRIM37 isoform X3

    15. XM_063799051.1 → XP_063655121.1  E3 ubiquitin-protein ligase TRIM37 isoform X24

    16. XM_063799052.1 → XP_063655122.1  E3 ubiquitin-protein ligase TRIM37 isoform X24

    17. XM_054670503.2 → XP_054526478.1  E3 ubiquitin-protein ligase TRIM37 isoform X12

    18. XM_063799065.1 → XP_063655135.1  E3 ubiquitin-protein ligase TRIM37 isoform X36

    19. XM_063799059.1 → XP_063655129.1  E3 ubiquitin-protein ligase TRIM37 isoform X31

    20. XM_063799062.1 → XP_063655132.1  E3 ubiquitin-protein ligase TRIM37 isoform X33

    21. XM_063799046.1 → XP_063655116.1  E3 ubiquitin-protein ligase TRIM37 isoform X15

    22. XM_054670505.2 → XP_054526480.1  E3 ubiquitin-protein ligase TRIM37 isoform X18

    23. XM_054670501.2 → XP_054526476.1  E3 ubiquitin-protein ligase TRIM37 isoform X9

    24. XM_016930833.2 → XP_016786322.1  E3 ubiquitin-protein ligase TRIM37 isoform X7

    25. XM_009432938.3 → XP_009431213.2  E3 ubiquitin-protein ligase TRIM37 isoform X8

    26. XM_016930830.2 → XP_016786319.1  E3 ubiquitin-protein ligase TRIM37 isoform X2

    27. XM_016930829.2 → XP_016786318.1  E3 ubiquitin-protein ligase TRIM37 isoform X1

    28. XM_063799043.1 → XP_063655113.1  E3 ubiquitin-protein ligase TRIM37 isoform X6

    29. XM_016930832.3 → XP_016786321.1  E3 ubiquitin-protein ligase TRIM37 isoform X5

    30. XM_063799058.1 → XP_063655128.1  E3 ubiquitin-protein ligase TRIM37 isoform X30

    31. XM_063799053.1 → XP_063655123.1  E3 ubiquitin-protein ligase TRIM37 isoform X24

    32. XM_063799063.1 → XP_063655133.1  E3 ubiquitin-protein ligase TRIM37 isoform X34

    33. XM_063799055.1 → XP_063655125.1  E3 ubiquitin-protein ligase TRIM37 isoform X26

      UniProtKB/TrEMBL
      A0A2I3TNT9

    34. XM_063799054.1 → XP_063655124.1  E3 ubiquitin-protein ligase TRIM37 isoform X25

    35. XM_063799061.1 → XP_063655131.1  E3 ubiquitin-protein ligase TRIM37 isoform X32

    36. XM_054670510.2 → XP_054526485.1  E3 ubiquitin-protein ligase TRIM37 isoform X28

    37. XM_063799070.1 → XP_063655140.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    38. XM_063799067.1 → XP_063655137.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    39. XM_024350689.3 → XP_024206457.1  E3 ubiquitin-protein ligase TRIM37 isoform X10

      Conserved Domains (4) summary
      smart00502
      Location:132 → 254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91 → 132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273 → 406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:13 → 55
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins

    40. XM_054670508.2 → XP_054526483.1  E3 ubiquitin-protein ligase TRIM37 isoform X24

    41. XM_063799056.1 → XP_063655126.1  E3 ubiquitin-protein ligase TRIM37 isoform X27

    42. XM_009432937.5 → XP_009431212.1  E3 ubiquitin-protein ligase TRIM37 isoform X19

      UniProtKB/TrEMBL
      A0A2J8MF05, A0A6D2W8G2, H2QDJ7
      Related
      ENSPTRP00000016064.4
      Conserved Domains (4) summary
      smart00502
      Location:98 → 220
      BBC; B-Box C-terminal domain
      smart00336
      Location:57 → 98
      BBOX; B-Box-type zinc finger
      cd03773
      Location:239 → 372
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cl17238
      Location:6 → 21
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    43. XM_024350691.3 → XP_024206459.1  E3 ubiquitin-protein ligase TRIM37 isoform X17

      Conserved Domains (4) summary
      smart00502
      Location:98 → 220
      BBC; B-Box C-terminal domain
      smart00336
      Location:57 → 98
      BBOX; B-Box-type zinc finger
      cd03773
      Location:239 → 372
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cl17238
      Location:6 → 21
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    44. XM_063799057.1 → XP_063655127.1  E3 ubiquitin-protein ligase TRIM37 isoform X29

    45. XM_063799064.1 → XP_063655134.1  E3 ubiquitin-protein ligase TRIM37 isoform X35

    46. XM_063799066.1 → XP_063655136.1  E3 ubiquitin-protein ligase TRIM37 isoform X35

    47. XM_063799073.1 → XP_063655143.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    48. XM_063799074.1 → XP_063655144.1  E3 ubiquitin-protein ligase TRIM37 isoform X37

    Nucleotide Protein
    Heading Accession and Version

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