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    FGFR3 fibroblast growth factor receptor 3 [ Terrapene triunguis (Three-toed box turtle) ]

    Gene ID: 112106019, updated on 28-Nov-2024

    Summary

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    Gene symbol
    FGFR3
    Gene description
    fibroblast growth factor receptor 3
    See related
    Ensembl:ENSTMTG00000002395
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Terrapene triunguis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Terrapene
    Orthologs
    human mouse all
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    Genomic context

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    See FGFR3 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    102 current T_m_triunguis-2.0 (GCF_002925995.2) Unplaced Scaffold NW_020664417.1 (87049579..87124261, complement)
    100 previous assembly T_m_triunguis-1.0 (GCF_002925995.1) Unplaced Scaffold NW_019959786.1 (480800..562897, complement)

    NW_020664417.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding SET domain protein 2 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 1 Neighboring gene transmembrane protein 129, E3 ubiquitin ligase Neighboring gene transforming acidic coiled-coil containing protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fibroblast growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fibroblast growth factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fibroblast growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fibroblast growth factor receptor 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Terrapene carolina triunguis Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T_m_triunguis-2.0

    Genomic

    1. NW_020664417.1 Reference T_m_triunguis-2.0

      Range
      87049579..87124261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024199050.2 → XP_024054818.1  fibroblast growth factor receptor 3 isoform X6

      UniProtKB/TrEMBL
      A0A674I530
      Related
      ENSTMTP00000003178.1, ENSTMTT00000003296.1
      Conserved Domains (4) summary
      cd05857
      Location:179 → 263
      Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
      cd05858
      Location:286 → 375
      Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
      cd05100
      Location:474 → 807
      PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
      smart00408
      Location:77 → 136
      IGc2; Immunoglobulin C-2 Type

    2. XM_024199049.2 → XP_024054817.1  fibroblast growth factor receptor 3 isoform X5

      Conserved Domains (4) summary
      cd05857
      Location:179 → 263
      Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
      cd05858
      Location:286 → 375
      Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
      cd05100
      Location:475 → 808
      PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
      smart00408
      Location:77 → 136
      IGc2; Immunoglobulin C-2 Type

    3. XM_024199047.2 → XP_024054815.1  fibroblast growth factor receptor 3 isoform X3

      Conserved Domains (4) summary
      cd05857
      Location:179 → 263
      Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
      cd05858
      Location:286 → 375
      Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
      cd05100
      Location:476 → 809
      PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
      smart00408
      Location:77 → 136
      IGc2; Immunoglobulin C-2 Type

    4. XM_024199048.2 → XP_024054816.1  fibroblast growth factor receptor 3 isoform X4

      UniProtKB/TrEMBL
      A0A674I1G7
      Related
      ENSTMTP00000003171.1, ENSTMTT00000003289.1
      Conserved Domains (4) summary
      cd05857
      Location:179 → 263
      Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
      cd05100
      Location:476 → 809
      PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
      smart00408
      Location:77 → 136
      IGc2; Immunoglobulin C-2 Type
      cd04974
      Location:286 → 374
      Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)

    5. XM_024199046.2 → XP_024054814.1  fibroblast growth factor receptor 3 isoform X2

      Conserved Domains (4) summary
      cd05857
      Location:179 → 263
      Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
      cd05100
      Location:477 → 810
      PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
      smart00408
      Location:77 → 136
      IGc2; Immunoglobulin C-2 Type
      cd04974
      Location:286 → 374
      Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)

    6. XM_024199045.2 → XP_024054813.1  fibroblast growth factor receptor 3 isoform X1

      Conserved Domains (4) summary
      cd05857
      Location:179 → 263
      Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
      cd05100
      Location:478 → 811
      PTKc_FGFR3; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 3
      smart00408
      Location:77 → 136
      IGc2; Immunoglobulin C-2 Type
      cd04974
      Location:286 → 374
      Ig3_FGFR; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    Nucleotide Protein
    Heading Accession and Version

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