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    ceh-39 Homeobox protein ceh-39 [ Caenorhabditis elegans ]

    Gene ID: 180505, updated on 9-Dec-2024

    Summary

    Official Symbol
    ceh-39
    Official Full Name
    Homeobox protein ceh-39
    Primary source
    WormBase:WBGene00000460
    Locus tag
    CELE_T26C11.7
    See related
    AllianceGenome:WB:WBGene00000460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and primary sex determination. Located in condensed nuclear chromosome and germ cell nucleus. Is expressed in body wall musculature; germ line; gonad; neurons; and ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ceh-39 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (1853874..1856172, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Homeobox protein ceh-21 Neighboring gene Secreted protein Neighboring gene ncRNA Neighboring gene tRNA-Glu

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in primary sex determination IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in condensed nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Homeobox protein ceh-39
    NP_508342.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      1853874..1856172 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075941.8NP_508342.1  Homeobox protein ceh-39 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508342.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22812
      Conserved Domains (2) summary
      smart00389
      Location:318371
      HOX; Homeodomain
      pfam02376
      Location:210286
      CUT; CUT domain