FXR1 FMR1 autosomal homolog 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: FXR1provided by CGNC
Full Name: FMR1 autosomal homolog 1provided by CGNC
Primary source: CGNC:52301
See related: Ensembl:ENSGALG00010016652
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	9	NC_052540.1 (16792149..16822854, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	9	NC_052581.1 (16584207..16614917, complement)

Chromosome 9 - NC_052540.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables mRNA 3'-UTR binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables translation regulator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA damage response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in anterograde axonal transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in central nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of translation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of translation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of dendrite morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of dendritic spine development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of filopodium assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of mRNA stability	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of modification of synaptic structure	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of translation at postsynapse, modulating synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info	PubMed
located_in dendritic filopodium	IEA Inferred from Electronic Annotation more info	PubMed
located_in dendritic spine	IEA Inferred from Electronic Annotation more info	PubMed
located_in dendritic spine neck	IEA Inferred from Electronic Annotation more info	PubMed
located_in growth cone	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuronal cell body	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuronal ribonucleoprotein granule	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
located_in postsynaptic density	IEA Inferred from Electronic Annotation more info	PubMed
located_in presynapse	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: RNA-binding protein FXR1; fragile X mental retardation syndrome-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012601.2 → NP_001012619.1 RNA-binding protein FXR1

See identical proteins and their annotated locations for NP_001012619.1

Status: PROVISIONAL

Source sequence(s)

AJ851574

UniProtKB/TrEMBL

A0A8V0YYV0, F1NN51, Q5F3S6

Related

ENSGALP00010023288.1, ENSGALT00010040173.1

Conserved Domains (5) summary

cd00105
Location:286 → 352

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam05641
Location:62 → 118

Agenet; Agenet domain

pfam12235
Location:354 → 465

FXMRP1_C_core; Fragile X-related 1 protein core C terminal

pfam16096
Location:491 → 564

FXR_C1; Fragile X-related 1 protein C-terminal region 2

pfam16097
Location:583 → 649

FXR_C3; Fragile X-related 1 protein C-terminal region 3

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

16792149..16822854 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015291423.4 → XP_015146909.1 fragile X mental retardation syndrome-related protein 1 isoform X5

UniProtKB/TrEMBL

A0A8V0YYV0

Conserved Domains (5) summary

cd00105
Location:286 → 352

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam05641
Location:62 → 118

Agenet; Agenet domain

pfam12235
Location:354 → 426

FXMRP1_C_core; Fragile X-related 1 protein core C terminal

pfam16096
Location:452 → 524

FXR_C1; Fragile X-related 1 protein C-terminal region 2

pfam16097
Location:571 → 637

FXR_C3; Fragile X-related 1 protein C-terminal region 3
XM_025153379.3 → XP_025009147.1 fragile X mental retardation syndrome-related protein 1 isoform X6

UniProtKB/TrEMBL

A0A8V0YYV0

Conserved Domains (6) summary

cd00105
Location:220 → 280

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam00013
Location:286 → 352

KH_1; KH domain

pfam05641
Location:62 → 117

Agenet; Agenet domain

pfam12235
Location:354 → 438

FXMRP1_C_core; Fragile X-related 1 protein core C terminal

pfam16096
Location:464 → 537

FXR_C1; Fragile X-related 1 protein C-terminal region 2

pfam16097
Location:556 → 622

FXR_C3; Fragile X-related 1 protein C-terminal region 3
XM_015291422.4 → XP_015146908.1 fragile X mental retardation syndrome-related protein 1 isoform X3

UniProtKB/TrEMBL

A0A8V0YYV0, A0A8V0YYW1

Related

ENSGALP00010023298.1, ENSGALT00010040190.1

Conserved Domains (5) summary

cd00105
Location:286 → 352

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam05641
Location:62 → 118

Agenet; Agenet domain

pfam12235
Location:354 → 438

FXMRP1_C_core; Fragile X-related 1 protein core C terminal

pfam16096
Location:464 → 536

FXR_C1; Fragile X-related 1 protein C-terminal region 2

pfam16097
Location:583 → 649

FXR_C3; Fragile X-related 1 protein C-terminal region 3
XM_025153378.3 → XP_025009146.1 fragile X mental retardation syndrome-related protein 1 isoform X4

UniProtKB/TrEMBL

A0A8V0YYV0

Conserved Domains (6) summary

cd00105
Location:220 → 280

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam00013
Location:286 → 352

KH_1; KH domain

pfam05641
Location:62 → 117

Agenet; Agenet domain

pfam12235
Location:354 → 453

FXMRP1_C_core; Fragile X-related 1 protein core C terminal

pfam16096
Location:479 → 552

FXR_C1; Fragile X-related 1 protein C-terminal region 2

pfam16097
Location:571 → 637

FXR_C3; Fragile X-related 1 protein C-terminal region 3
XM_015291421.4 → XP_015146907.1 fragile X mental retardation syndrome-related protein 1 isoform X2

UniProtKB/TrEMBL

A0A8V0YYV0

Conserved Domains (5) summary

cd00105
Location:286 → 352

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam05641
Location:62 → 118

Agenet; Agenet domain

pfam12235
Location:354 → 453

FXMRP1_C_core; Fragile X-related 1 protein core C terminal

pfam16096
Location:479 → 551

FXR_C1; Fragile X-related 1 protein C-terminal region 2

pfam16097
Location:598 → 664

FXR_C3; Fragile X-related 1 protein C-terminal region 3
XM_015291420.4 → XP_015146906.1 fragile X mental retardation syndrome-related protein 1 isoform X1

UniProtKB/TrEMBL

A0A8V0YXD7, A0A8V0YYV0

Related

ENSGALP00010023299.1, ENSGALT00010040191.1

Conserved Domains (5) summary

cd00105
Location:286 → 352

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

pfam05641
Location:62 → 118

Agenet; Agenet domain

pfam12235
Location:354 → 465

FXMRP1_C_core; Fragile X-related 1 protein core C terminal

pfam16096
Location:491 → 563

FXR_C1; Fragile X-related 1 protein C-terminal region 2

pfam16097
Location:610 → 676

FXR_C3; Fragile X-related 1 protein C-terminal region 3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

16584207..16614917 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046923911.1 → XP_046779867.1 fragile X mental retardation syndrome-related protein 1 isoform X5

UniProtKB/TrEMBL

A0A8V0YYV0
XM_046923912.1 → XP_046779868.1 fragile X mental retardation syndrome-related protein 1 isoform X6

UniProtKB/TrEMBL

A0A8V0YYV0
XM_046923909.1 → XP_046779865.1 fragile X mental retardation syndrome-related protein 1 isoform X3

UniProtKB/TrEMBL

A0A8V0YYV0, A0A8V0YYW1
XM_046923910.1 → XP_046779866.1 fragile X mental retardation syndrome-related protein 1 isoform X4

UniProtKB/TrEMBL

A0A8V0YYV0
XM_046923908.1 → XP_046779864.1 fragile X mental retardation syndrome-related protein 1 isoform X2

UniProtKB/TrEMBL

A0A8V0YYV0
XM_046923907.1 → XP_046779863.1 fragile X mental retardation syndrome-related protein 1 isoform X1

UniProtKB/TrEMBL

A0A8V0YXD7, A0A8V0YYV0