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    CPEB1 cytoplasmic polyadenylation element binding protein 1 [ Homo sapiens (human) ]

    Gene ID: 64506, updated on 27-Nov-2024

    Summary

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    Official Symbol
    CPEB1provided by HGNC
    Official Full Name
    cytoplasmic polyadenylation element binding protein 1provided by HGNC
    Primary source
    HGNC:HGNC:21744
    See related
    Ensembl:ENSG00000214575 MIM:607342; AllianceGenome:HGNC:21744
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CPEB; CPEB-1; h-CPEB; CPE-BP1; hCPEB-1
    Summary
    This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
    Expression
    Biased expression in testis (RPKM 19.2), brain (RPKM 6.3) and 8 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See CPEB1 in Genome Data Viewer
    Location:
    15q25.2
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (82543201..82648795, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (80407439..80513020, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (83211951..83317546, complement)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6748 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6749 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:82825221-82825722 Neighboring gene dynamin 1 pseudogene 38 Neighboring gene ribosomal protein S17 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6750 Neighboring gene CPEB1 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 5793 Neighboring gene adaptor related protein complex 3 subunit beta 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6751 Neighboring gene serine and arginine rich splicing factor 9 pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr15:83362511-83362661 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:83367432-83368224 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:83368225-83369015 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6752 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6753 Neighboring gene epididymal protein pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease. Picó S, et al. Sci Transl Med, 2021 Sep 29. PMID 34586830
    2. Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression. Sovijit W, et al. Biochem Biophys Res Commun, 2021 Jan 1. PMID 33162033
    3. Energy landscapes of a mechanical prion and their implications for the molecular mechanism of long-term memory. Chen M, et al. Proc Natl Acad Sci U S A, 2016 May 3. PMID 27091989, Free PMC Article
    4. CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort. Jiao W, et al. J Ovarian Res, 2020 Apr 30. PMID 32354341, Free PMC Article
    5. Specificity factors in cytoplasmic polyadenylation. Charlesworth A, et al. Wiley Interdiscip Rev RNA, 2013 Jul-Aug. PMID 23776146, Free PMC Article

    See all (61) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CPEB1 Controls NRF2 Proteostasis and Ferroptosis Susceptibility in Pancreatic Cancer.
      Title: CPEB1 Controls NRF2 Proteostasis and Ferroptosis Susceptibility in Pancreatic Cancer.
    2. DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter.
      Title: DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter.
    3. CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.
      Title: CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.
    4. Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression.
      Title: Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression.
    5. CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort.
      Title: CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort.
    6. CPEB1 and CPEB4 are involved in the regulation of the TAK1 and Smad signalings in human macrophages and dermal fibroblasts
      Title: CPEB1 or CPEB4 knockdown suppresses the TAK1 and Smad signalings in THP-1 macrophage-like cells and dermal fibroblasts.
    7. Study revealed that CPEB1 depletion might play an anti-inflammatory and antiapoptotic role in Ox-LDL-induced apoptosis and inflammation though SIRT1/LOX-1 signalling pathway.
      Title: Depletion of CPEB1 protects against oxidized LDL-induced endothelial apoptosis and inflammation though SIRT1/LOX-1 signalling pathway.
    8. study identifies CPEB1 as a potential regulator of disease progression of Posttraumatic Ankle Osteoarthritis
      Title: CPEB1 Expression Correlates with Severity of Posttraumatic Ankle Osteoarthritis and Aggravates Catabolic Effect of IL-1β on Chondrocytes.
    9. These findings indicated that the overexpression of miR4543p inhibited cell proliferation, migration and invasion by downregulating CPEB1.
      Title: miR‑454‑3p suppresses cell migration and invasion by targeting CPEB1 in human glioblastoma.
    10. Upon binding to p27(Kip1) 3'UTR, CPEB1 promotes elongation of poly-A tail and the subsequent translation of p27(Kip1) mRNA. This leads to higher levels of p27(Kip1) in the cell, in turn significantly inhibiting cell proliferation, and confers to CPEB1 a potential value as a tumor suppressor in Glioblastoma.
      Title: CPEB1 restrains proliferation of Glioblastoma cells through the regulation of p27(Kip1) mRNA translation.
    Submit: New GeneRIF Correction See all GeneRIFs (36)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Potential readthrough

    Included gene: RPS17

    Homology

    Clone Names

    • FLJ13203, MGC34136, MGC60106

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables mRNA 3'-UTR AU-rich region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA regulatory element binding translation repressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA regulatory element binding translation repressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation factor activity, RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to amino acid stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cellular response to hypoxia IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cellular response to insulin stimulus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of cytoplasmic translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of mRNA 3'-end processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cytoplasmic polyadenylation element-binding protein 1
    Names
    CPE-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079533.2 → NP_001073001.1  cytoplasmic polyadenylation element-binding protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001073001.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2), also known as short, contains a distinct 5' UTR, lacks an in-frame portion of the 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus and lacks a central 5 aa segment, compared to isoform 1. Variants 2 and 25 both encode the same isoform (2).
      Source sequence(s)
      AC010724, AF329403, AL832156
      Consensus CDS
      CCDS42072.2
      UniProtKB/Swiss-Prot
      B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
      Related
      ENSP00000483590.1, ENST00000618449.4
      Conserved Domains (4) summary
      pfam16366
      Location:429 → 484
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 341
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:352 → 435
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    2. NM_001079534.2 → NP_001073002.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      See identical proteins and their annotated locations for NP_001073002.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3-5, 11-16, and 26-32 all encode the same isoform (3).
      Source sequence(s)
      AC010724, AF329403, AK023265, AL832156, DA705313
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Related
      ENSP00000483857.1, ENST00000611163.4
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    3. NM_001079535.2 → NP_001073003.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      See identical proteins and their annotated locations for NP_001073003.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3-5, 11-16, and 26-32 all encode the same isoform (3).
      Source sequence(s)
      AC010724, AF329403, AL832156, BC035348, DA340952, DA705313
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Related
      ENSP00000477557.1, ENST00000617462.4
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    4. NM_001288819.2 → NP_001275748.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      See identical proteins and their annotated locations for NP_001275748.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3-5, 11-16, and 26-32 all encode the same isoform (3).
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Related
      ENSP00000484549.1, ENST00000620182.4
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    5. NM_001288820.2 → NP_001275749.1  cytoplasmic polyadenylation element-binding protein 1 isoform 4

      See identical proteins and their annotated locations for NP_001275749.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1. Variants 6, 34, and 35 all encode the same isoform (4).
      Source sequence(s)
      AK301728, AL832156, BM715948, BX649159, HY191346
      UniProtKB/TrEMBL
      B4DWY2
      Conserved Domains (4) summary
      pfam16366
      Location:273 → 328
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 81
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:83 → 185
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:196 → 279
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    6. NM_001365240.1 → NP_001352169.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    7. NM_001365241.1 → NP_001352170.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Related
      ENSP00000481010.1, ENST00000614918.4
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    8. NM_001365242.1 → NP_001352171.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Related
      ENSP00000507835.1, ENST00000684509.1
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    9. NM_001365243.1 → NP_001352172.1  cytoplasmic polyadenylation element-binding protein 1 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      UniProtKB/Swiss-Prot
      B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
      Related
      ENSP00000478598.1, ENST00000617958.4
      Conserved Domains (4) summary
      cd12723
      Location:309 → 416
      RRM1_CPEB1; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:427 → 512
      RRM2_CPEB1; RNA recognition motif 2 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      pfam16366
      Location:504 → 559
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 307
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus

    10. NM_001365244.1 → NP_001352173.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    11. NM_001365245.1 → NP_001352174.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    12. NM_001365246.1 → NP_001352175.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    13. NM_001365247.1 → NP_001352176.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    14. NM_001365248.1 → NP_001352177.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    15. NM_001365249.1 → NP_001352178.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    16. NM_001365250.1 → NP_001352179.1  cytoplasmic polyadenylation element-binding protein 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC245033
      Consensus CDS
      CCDS42072.2
      UniProtKB/Swiss-Prot
      B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
      Conserved Domains (4) summary
      pfam16366
      Location:429 → 484
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 341
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:352 → 435
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    17. NM_001387061.1 → NP_001373990.1  cytoplasmic polyadenylation element-binding protein 1 isoform 7

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18) encodes the longest isoform (7).
      Source sequence(s)
      AC105339, AC110291, AC245033
      UniProtKB/Swiss-Prot
      B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
      Conserved Domains (4) summary
      pfam16366
      Location:531 → 586
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 443
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:454 → 537
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    18. NM_001387062.1 → NP_001373991.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variants 7-9 and 20-24, encodes isoform 5.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    19. NM_001387063.1 → NP_001373992.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 7-9, 19, and 21-24, encodes isoform 5.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    20. NM_001387064.1 → NP_001373993.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 7-9, 19, 20, and 22-24, encodes isoform 5.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    21. NM_001387065.1 → NP_001373994.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variants 7-9, 19-21, 23, and 24, encodes isoform 5.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    22. NM_001387066.1 → NP_001373995.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23), as well as variants 7-9, 19-22, and 24, encodes isoform 5.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    23. NM_001387067.1 → NP_001373996.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24), as well as variants 7-9 and 19-23, encodes isoform 5.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS92050.1
      UniProtKB/TrEMBL
      A0A087WXG7, A0A087X171
      Conserved Domains (4) summary
      pfam16366
      Location:526 → 581
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:31 → 334
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:336 → 438
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:449 → 532
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    24. NM_001387068.1 → NP_001373997.1  cytoplasmic polyadenylation element-binding protein 1 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25), as well as variant 2, encodes isoform (2).
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS42072.2
      UniProtKB/Swiss-Prot
      B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
      Conserved Domains (4) summary
      pfam16366
      Location:429 → 484
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 341
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:352 → 435
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    25. NM_001387069.1 → NP_001373998.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (26), as well as variants 3-5, 11-16, and 27-32, encodes isoform 3.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    26. NM_001387070.1 → NP_001373999.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (27), as well as variants 3-5, 11-16, 26, and 28-32, encodes isoform 3.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    27. NM_001387071.1 → NP_001374000.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (28), as well as variants 3-5, 11-16, 26, 27, and 29-32, encodes isoform 3.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    28. NM_001387072.1 → NP_001374001.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (29), as well as variants 3-5, 11-16, 26-28, and 30-32, encodes isoform 3.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    29. NM_001387073.1 → NP_001374002.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (30), as well as variants 3-5, 11-16, 26-29, 31 and 32, encodes isoform 3.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    30. NM_001387074.1 → NP_001374003.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (31), as well as variants 3-5, 11-16, 26-30, and 32, encodes isoform 3.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    31. NM_001387075.1 → NP_001374004.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (32), as well as variants 3-5, 11-16, and 26-31, encodes isoform 3.
      Source sequence(s)
      AC105339, AC110291, AC245033
      Consensus CDS
      CCDS45330.2
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:424 → 479
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 336
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:347 → 430
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    32. NM_001387076.1 → NP_001374005.1  cytoplasmic polyadenylation element-binding protein 1 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC105339, AC110291, AC245033
      UniProtKB/TrEMBL
      A0A0J9YXP0
      Conserved Domains (4) summary
      pfam16366
      Location:412 → 467
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 232
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:234 → 324
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:335 → 418
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    33. NM_001387077.1 → NP_001374006.1  cytoplasmic polyadenylation element-binding protein 1 isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (34), as well as variants 6 and 35, encodes isoform 4.
      Source sequence(s)
      AC245033
      UniProtKB/TrEMBL
      B4DWY2
      Conserved Domains (4) summary
      pfam16366
      Location:273 → 328
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 81
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:83 → 185
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:196 → 279
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    34. NM_001387078.1 → NP_001374007.1  cytoplasmic polyadenylation element-binding protein 1 isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (35), as well as variants 6 and 34, encodes isoform 4.
      Source sequence(s)
      AC245033
      UniProtKB/TrEMBL
      B4DWY2
      Conserved Domains (4) summary
      pfam16366
      Location:273 → 328
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 81
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
      cd12723
      Location:83 → 185
      RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:196 → 279
      RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

    35. NM_030594.5 → NP_085097.3  cytoplasmic polyadenylation element-binding protein 1 isoform 1

      See identical proteins and their annotated locations for NP_085097.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AC105339, AL832156, BC050629, BM715948, BX649159, HY007452, HY191346
      Consensus CDS
      CCDS45329.2
      UniProtKB/TrEMBL
      A0A087X171
      Related
      ENSP00000477715.1, ENST00000615198.4
      Conserved Domains (4) summary
      cd12723
      Location:309 → 411
      RRM1_CPEB1; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      cd12725
      Location:422 → 507
      RRM2_CPEB1; RNA recognition motif 2 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
      pfam16366
      Location:499 → 554
      CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
      pfam16368
      Location:1 → 307
      CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      82543201..82648795 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_187606.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      332306..430793 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      80407439..80513020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BZB8.1 GenPept UniProtKB/Swiss-Prot:Q9BZB8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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