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    ipo7.L importin 7 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 379321, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ipo7.L
    Official Full Name
    importin 7 L homeolog
    Primary source
    Xenbase:XB-GENE-919785
    Locus tag
    XELAEV_18021791mg
    See related
    EnsemblRapid:ENSXLAG00005021291 AllianceGenome:Xenbase:XB-GENE-919785
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    imp7; ipo7; ranbp7
    Summary
    Predicted to enable small GTPase binding activity. Acts upstream of or within ribosomal protein import into nucleus. Predicted to be located in cytosol and nuclear envelope. Is expressed in ectoderm; nervous system; pharyngeal arch; sensory system; and visual system. Orthologous to human IPO7 (importin 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ipo7.L in Genome Data Viewer
    Location:
    chromosome: 4L
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (4709676..4742477)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (4785630..4807238)

    Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene BTB (POZ) domain containing 10 L homeolog Neighboring gene uncharacterized LOC108713743 Neighboring gene small nucleolar RNA SNORA23 Neighboring gene small nucleolar RNA SNORA23 Neighboring gene transmembrane protein 41B L homeolog Neighboring gene zinc finger protein 143 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional comparison of H1 histones in Xenopus reveals isoform-specific regulation by Cdk1 and RanGTP. Freedman BS, et al. Curr Biol, 2010 Jun 8. PMID 20471264, Free PMC Article
    2. A novel class of RanGTP binding proteins. Görlich D, et al. J Cell Biol, 1997 Jul 14. PMID 9214382, Free PMC Article
    3. Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. Jäkel S, et al. EMBO J, 1998 Aug 3. PMID 9687515, Free PMC Article
    4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC52556, MGC132350

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosomal protein import into nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    importin 7 L homeolog
    Names
    RAN binding protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001086165.1 → NP_001079634.1  importin 7 L homeolog

      See identical proteins and their annotated locations for NP_001079634.1

      Status: PROVISIONAL

      Source sequence(s)
      U71082
      UniProtKB/TrEMBL
      A0A974D135, O42480
      Related
      ENSXLAP00005062488.1, ENSXLAT00005063941.1
      Conserved Domains (1) summary
      COG5656
      Location:15 → 997
      SXM1; Importin, protein involved in nuclear import [Posttranslational modification, protein turnover, chaperones]

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      4709676..4742477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041589134.1 → XP_041445068.1  importin 7 L homeolog isoform X1

      UniProtKB/TrEMBL
      A0A974D135, Q7ZWZ8
      Conserved Domains (1) summary
      COG5656
      Location:15 → 996
      SXM1; Importin, protein involved in nuclear import [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein Strain
    Heading Accession and Version

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