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    Ankrd37 ankyrin repeat domain 37 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361149, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ankrd37provided by RGD
    Official Full Name
    ankyrin repeat domain 37provided by RGD
    Primary source
    RGD:1565715
    See related
    EnsemblRapid:ENSRNOG00000031335 AllianceGenome:RGD:1565715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565715
    Summary
    Predicted to be located in cytosol; mitochondrion; and nucleus. Predicted to be active in cytoplasm. Orthologous to human ANKRD37 (ankyrin repeat domain 37). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 75.0), Thymus (RPKM 27.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ankrd37 in Genome Data Viewer
    Location:
    16q11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (53001487..53004545)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (46268933..46271971)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (49463016..49465905)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 97 Neighboring gene sorting nexin 25 Neighboring gene U6 spliceosomal RNA Neighboring gene Lrp2 binding protein Neighboring gene UFM1-specific peptidase 2 Neighboring gene cilia and flagella associated protein 96 Neighboring gene coiled-coil domain containing 110

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mouse Fem1b interacts with and induces ubiquitin-mediated degradation of Ankrd37. Shi YQ, et al. Gene, 2011 Oct 10. PMID 21723927
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in male germ cell nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 37

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108400.3 → NP_001101870.1  ankyrin repeat domain-containing protein 37

      See identical proteins and their annotated locations for NP_001101870.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      B2RYS4, F7EMG3
      Related
      ENSRNOP00000088167.2, ENSRNOT00000120066.2
      Conserved Domains (3) summary
      cd00204
      Location:10 → 116
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam13637
      Location:66 → 116
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:30 → 61
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      53001487..53004545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275515.1 → XP_063131585.1  ankyrin repeat domain-containing protein 37 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A8T4, F7EMG3

    2. XM_039094639.2 → XP_038950567.1  ankyrin repeat domain-containing protein 37 isoform X2

      UniProtKB/TrEMBL
      A6JPQ1
      Conserved Domains (2) summary
      sd00045
      Location:30 → 61
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:36 → 85
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_063275516.1 → XP_063131586.1  ankyrin repeat domain-containing protein 37 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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