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    Tmem120b transmembrane protein 120B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690137, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tmem120bprovided by RGD
    Official Full Name
    transmembrane protein 120Bprovided by RGD
    Primary source
    RGD:1584031
    See related
    EnsemblRapid:ENSRNOG00000048050 AllianceGenome:RGD:1584031
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in fat cell differentiation and protein heterooligomerization. Predicted to be active in nuclear inner membrane. Orthologous to human TMEM120B (transmembrane protein 120B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 46.0), Thymus (RPKM 35.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem120b in Genome Data Viewer
    Location:
    12q16
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (39108280..39148090, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (33447441..33487257, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (38894847..38916237, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene SET domain containing 1B, histone lysine methyltransferase Neighboring gene ras homolog family member F, filopodia associated Neighboring gene ribosomal protein L32, pseudogene 9 Neighboring gene MORN repeat containing 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables monoatomic ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in fat cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein heterooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in nuclear inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear inner membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271309.2NP_001258238.1  transmembrane protein 120B

      See identical proteins and their annotated locations for NP_001258238.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A0A8I5ZLE9, A6J168, M0R6Y6
      Related
      ENSRNOP00000065199.2, ENSRNOT00000074517.5
      Conserved Domains (1) summary
      pfam07851
      Location:9332
      TMPIT; TMPIT-like protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      39108280..39148090 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_005491673.1 RNA Sequence