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    FXR1 FMR1 autosomal homolog 1 [ Balaenoptera acutorostrata (minke whale) ]

    Gene ID: 103020102, updated on 11-Mar-2024

    Summary

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    Gene symbol
    FXR1
    Gene description
    FMR1 autosomal homolog 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Balaenoptera acutorostrata
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera
    Orthologs
    human mouse all
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    Genomic context

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    See FXR1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2023_06 current mBalAcu1.1 (GCF_949987535.1) 4 NC_080067.1 (64613186..64670155)
    101 previous assembly BalAcu1.0 (GCF_000493695.1) Unplaced Scaffold NW_006733123.1 (12975808..13032816, complement)

    Chromosome 4 - NC_080067.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain 39 molecular ruler complex subunit Neighboring gene coiled-coil domain-containing protein 90B, mitochondrial-like Neighboring gene DnaJ heat shock protein family (Hsp40) member C19 Neighboring gene protein lin-28 homolog A-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anterograde axonal transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of dendrite morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of dendritic spine development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of filopodium assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mRNA stability IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of modification of synaptic structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of translation at postsynapse, modulating synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic filopodium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine neck IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in growth cone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal ribonucleoprotein granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNA-binding protein FXR1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_949987535.1-RS_2023_06

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mBalAcu1.1

    Genomic

    1. NC_080067.1 Reference mBalAcu1.1

      Range
      64613186..64670155
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028162084.2 → XP_028017885.1  RNA-binding protein FXR1 isoform X1

      UniProtKB/TrEMBL
      A0A452C4M1
      Conserved Domains (8) summary
      pfam12235
      Location:354 → 465
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal
      pfam16096
      Location:491 → 564
      FXR_C1; Fragile X-related 1 protein C-terminal region 2
      pfam16097
      Location:610 → 676
      FXR_C3; Fragile X-related 1 protein C-terminal region 3
      cd20472
      Location:3 → 57
      Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd20475
      Location:61 → 126
      Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22504
      Location:123 → 199
      KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22507
      Location:218 → 280
      KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22510
      Location:281 → 358
      KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

    2. XM_028162085.1 → XP_028017886.1  RNA-binding protein FXR1 isoform X2

      UniProtKB/TrEMBL
      A0A452C4J9
      Conserved Domains (8) summary
      pfam12235
      Location:354 → 465
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal
      pfam16096
      Location:491 → 564
      FXR_C1; Fragile X-related 1 protein C-terminal region 2
      pfam16097
      Location:583 → 649
      FXR_C3; Fragile X-related 1 protein C-terminal region 3
      cd20472
      Location:3 → 57
      Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd20475
      Location:61 → 126
      Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22504
      Location:123 → 199
      KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22507
      Location:218 → 280
      KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22510
      Location:281 → 358
      KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

    3. XM_028162086.1 → XP_028017887.1  RNA-binding protein FXR1 isoform X3

      UniProtKB/TrEMBL
      A0A452C4C4
      Conserved Domains (8) summary
      pfam12235
      Location:354 → 436
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal
      pfam16096
      Location:462 → 535
      FXR_C1; Fragile X-related 1 protein C-terminal region 2
      pfam16097
      Location:581 → 647
      FXR_C3; Fragile X-related 1 protein C-terminal region 3
      cd20472
      Location:3 → 57
      Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd20475
      Location:61 → 126
      Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22504
      Location:123 → 199
      KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22507
      Location:218 → 280
      KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22510
      Location:281 → 358
      KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

    4. XM_028162087.1 → XP_028017888.1  RNA-binding protein FXR1 isoform X4

      UniProtKB/TrEMBL
      A0A452C447
      Conserved Domains (8) summary
      pfam12235
      Location:354 → 436
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal
      pfam16096
      Location:462 → 535
      FXR_C1; Fragile X-related 1 protein C-terminal region 2
      pfam16097
      Location:554 → 620
      FXR_C3; Fragile X-related 1 protein C-terminal region 3
      cd20472
      Location:3 → 57
      Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd20475
      Location:61 → 126
      Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22504
      Location:123 → 199
      KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22507
      Location:218 → 280
      KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22510
      Location:281 → 358
      KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

    5. XM_028162088.2 → XP_028017889.1  RNA-binding protein FXR1 isoform X5

      UniProtKB/TrEMBL
      A0A452C4L3
      Conserved Domains (7) summary
      pfam12235
      Location:354 → 465
      FXMRP1_C_core; Fragile X-related 1 protein core C terminal
      pfam16096
      Location:491 → 564
      FXR_C1; Fragile X-related 1 protein C-terminal region 2
      cd20472
      Location:3 → 57
      Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd20475
      Location:61 → 126
      Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22504
      Location:123 → 199
      KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22507
      Location:218 → 280
      KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
      cd22510
      Location:281 → 358
      KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    Nucleotide Protein
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