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    LOC1278292 sphingolipid delta(4)-desaturase DES1 [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1278292, updated on 22-Jun-2024

    Summary

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    Gene symbol
    LOC1278292
    Gene description
    sphingolipid delta(4)-desaturase DES1
    See related
    VectorBase:AGAMI1_003907
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Also known as
    AGAP011402
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    Genomic context

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    See LOC1278292 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 3 NC_064602.1 (81473585..81474949, complement)

    Chromosome 3 - NC_064602.1Genomic Context describing neighboring genes Neighboring gene protein angel Neighboring gene serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like Neighboring gene zinc finger protein 652-B Neighboring gene zinc finger protein 628

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064602.1 Chromosome 3 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingolipid delta-4 desaturase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingolipid delta(4)-desaturase DES1
    Names
    AGAP011402-PA
    sphingolipid delta-4 desaturase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064602.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      81473585..81474949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_317914.4 → XP_317914.3  sphingolipid delta(4)-desaturase DES1

      See identical proteins and their annotated locations for XP_317914.3

      UniProtKB/TrEMBL
      Q7Q2Y9
      Conserved Domains (2) summary
      cd03508
      Location:26 → 315
      Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
      pfam08557
      Location:6 → 42
      Lipid_DES; Sphingolipid Delta4-desaturase (DES)
    Nucleotide Protein Strain
    Heading Accession and Version

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