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    CCHa2-R CCHamide-2 receptor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35535, updated on 9-Dec-2024

    Summary

    Official Symbol
    CCHa2-Rprovided by FlyBase
    Official Full Name
    CCHamide-2 receptorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033058
    Locus tag
    Dmel_CG14593
    See related
    AllianceGenome:FB:FBgn0033058
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0131005.23; CCH2aR; CCHa2r; CCHa2R; CCHamide-2 R; CG14593; CG14594; Dmel\CG14593
    Summary
    Enables neuropeptide receptor activity. Involved in neuropeptide signaling pathway. Located in membrane. Is expressed in adult head; embryonic abdominal segment; larval central nervous system; larval insulin secreting cell of pars intercerebralis; and ventral midline of embryo. Orthologous to several human genes including BRS3 (bombesin receptor subtype 3) and GRPR (gastrin releasing peptide receptor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CCHa2-R in Genome Data Viewer
    Location:
    42A8-42A9; 2-55 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6050949..6068680)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1938454..1956185)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44130 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44131 Neighboring gene lethal (2) k09848

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled peptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables neuropeptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables neuropeptide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables neuropeptide receptor activity ISM
    Inferred from Sequence Model
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    CCHamide-2 receptor
    Names
    CCHa2-R-PA
    CCHa2-R-PB
    CCHa2-R-PC
    CG14593-PA
    CG14593-PB
    CG14593-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6050949..6068680
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136355.4NP_610199.2  CCHamide-2 receptor, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610199.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1Z6J7, A9UJU7, E1JGY1, Q4V622
      Conserved Domains (2) summary
      pfam00001
      Location:86349
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:77197
      7tm_4; Olfactory receptor
    2. NM_001369980.1NP_001356958.1  CCHamide-2 receptor, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4P7VJP0
      Conserved Domains (1) summary
      cd15927
      Location:70362
      7tmA_Bombesin_R-like; bombesin receptor subfamily, member of the class A family of seven-transmembrane G protein-coupled receptors
    3. NM_001169589.2NP_001163060.1  CCHamide-2 receptor, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163060.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V622
      Conserved Domains (2) summary
      pfam00001
      Location:86349
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:77197
      7tm_4; Olfactory receptor