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    Pkn Protein kinase N [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35950, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pknprovided by FlyBase
    Official Full Name
    Protein kinase Nprovided by FlyBase
    Primary source
    FLYBASE:FBgn0020621
    Locus tag
    Dmel_CG2049
    See related
    AllianceGenome:FB:FBgn0020621
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    3-2; CG2049; CG2055; CG8; CT6637; CT6660; Dmel\CG2049; dPKN; Dpkn; DPKN; l(2)06736; l(2)45Ca; Pk45C; Pk?3; PKC-related; pkn; PKN; PRK2; v(2)rG232
    Summary
    Enables protein kinase activity. Involved in several processes, including dorsal closure; mitotic cytokinesis, division site positioning; and protein autophosphorylation. Located in apical cortex. Is expressed in several structures, including adult brain cell body rind; adult head; embryonic/larval anterior spiracle; embryonic/larval mouth; and embryonic/larval pharynx. Orthologous to several human genes including PKN2 (protein kinase N2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Pkn in Genome Data Viewer
    Location:
    45C1-45C1; 2-60 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9252310..9285097, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5139815..5172602, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene hikaru genki Neighboring gene Cytochrome P450 4p1 Neighboring gene Cytochrome P450 4p3 Neighboring gene tRNA splicing endonuclease subunit 15 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45132 Neighboring gene uncharacterized protein Neighboring gene Component of oligomeric golgi complex 6 Neighboring gene Mitotic arrest-deficient 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a novel Drosophila protein kinase highly homologous to protein kinase N (PKN). Ueno N, et al. Biochem Biophys Res Commun, 1997 Mar 6. PMID 9125115
    2. Disruption of the protein kinase N gene of drosophila melanogaster results in the recessive delorean allele (pkndln) with a negative impact on wing morphogenesis. Sass GL, et al. G3 (Bethesda), 2014 Apr 16. PMID 24531729, Free PMC Article
    3. A rho-binding protein kinase C-like activity is required for the function of protein kinase N in Drosophila development. Betson M, et al. Genetics, 2007 Aug. PMID 17507675, Free PMC Article
    4. Protein kinase C (PKC) isoforms in Drosophila. Shieh BH, et al. J Biochem, 2002 Oct. PMID 12359065
    5. Identification and genetic analysis of wunen, a gene guiding Drosophila melanogaster germ cell migration. Zhang N, et al. Genetics, 1996 Jul. PMID 8807296, Free PMC Article

    See all (103) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. polarity-induced spatiotemporal control of Rok and Pkn is important for unequal cortical expansion, ensuring correct cleavage furrow positioning and the establishment of physical asymmetry.
      Title: Cell Polarity Regulates Biased Myosin Activity and Dynamics during Asymmetric Cell Division via Drosophila Rho Kinase and Protein Kinase N.
    2. The delorean phenotype, with its associated defects in wing morphology, provides evidence of a role for PKN in adult morphogenetic processes.
      Title: Disruption of the protein kinase N gene of drosophila melanogaster results in the recessive delorean allele (pkndln) with a negative impact on wing morphogenesis.
    3. Drosophila protein kinase N is a negative regulator of actin-myosin activity during oogenesis.
      Title: Drosophila protein kinase N (Pkn) is a negative regulator of actin-myosin activity during oogenesis.
    4. identified a requirement for Pkn in wing morphogenesis, thereby revealing the first postembryonic function for Pkn
      Title: A rho-binding protein kinase C-like activity is required for the function of protein kinase N in Drosophila development.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in dorsal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in dorsal closure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cytokinesis, division site positioning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of wound healing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in wing disc morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    protein kinase N
    Names
    CG2049-PB
    CG2049-PC
    CG2049-PD
    CG2049-PE
    CG2049-PF
    CG2049-PG
    CG2049-PH
    CG2049-PJ
    CG2049-PK
    CG2049-PL
    CG2049-PM
    CG2049-PN
    CG2049-PO
    CG2049-PP
    CG2049-PQ
    CG2049-PS
    Pkn-PB
    Pkn-PC
    Pkn-PD
    Pkn-PE
    Pkn-PF
    Pkn-PG
    Pkn-PH
    Pkn-PJ
    Pkn-PK
    Pkn-PL
    Pkn-PM
    Pkn-PN
    Pkn-PO
    Pkn-PP
    Pkn-PQ
    Pkn-PS
    complementation group 8
    protein kinase c related
    protein kinase related to protein kinase N
    protein kinase-like 45C
    NP_001097237.1
    NP_001163095.1
    NP_001188895.1
    NP_001188896.1
    NP_001188897.3
    NP_001246220.1
    NP_001246221.1
    NP_001286241.1
    NP_001286242.1
    NP_001286243.1
    NP_001286244.1
    NP_788290.1
    NP_788291.1
    NP_788292.1
    NP_788293.2
    NP_788294.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9252310..9285097 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176110.2 → NP_788290.1  protein kinase N, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788290.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1Z7T0, C7LA81
      Related
      FBpp0087682
      Conserved Domains (6) summary
      cd11622
      Location:37 → 100
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:149 → 215
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:246 → 320
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:863 → 1122
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:863 → 1188
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:436 → 517
      C2; C2 domain

    2. NM_176112.2 → NP_788292.1  protein kinase N, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788292.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z7T2
      Related
      FBpp0087684
      Conserved Domains (6) summary
      cd11622
      Location:52 → 115
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:164 → 230
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:261 → 335
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:878 → 1137
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:878 → 1203
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:451 → 532
      C2; C2 domain

    3. NM_176113.3 → NP_788293.2  protein kinase N, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788293.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z7T3
      Conserved Domains (6) summary
      cd11622
      Location:52 → 115
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:164 → 230
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:261 → 335
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:1095 → 1354
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:1095 → 1420
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:451 → 532
      C2; C2 domain

    4. NM_001169624.1 → NP_001163095.1  protein kinase N, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163095.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JH15
      Conserved Domains (6) summary
      cd11622
      Location:131 → 194
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:243 → 309
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:340 → 414
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:957 → 1216
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:957 → 1282
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:530 → 611
      C2; C2 domain

    5. NM_001201967.1 → NP_001188896.1  protein kinase N, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188896.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JD07, A0A0B4JD60
      Conserved Domains (6) summary
      cd11622
      Location:131 → 194
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:243 → 309
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:340 → 414
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:1027 → 1286
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:1027 → 1352
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:530 → 611
      C2; C2 domain

    6. NM_001103767.2 → NP_001097237.1  protein kinase N, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097237.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DY76
      Conserved Domains (6) summary
      cd11622
      Location:131 → 194
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:243 → 309
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:340 → 414
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:1174 → 1433
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:1174 → 1499
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:530 → 611
      C2; C2 domain

    7. NM_176114.3 → NP_788294.1  protein kinase N, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788294.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z7T4, Q7YU74
      Related
      FBpp0087686
      Conserved Domains (2) summary
      smart00220
      Location:263 → 522
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:263 → 588
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N

    8. NM_001299313.1 → NP_001286242.1  protein kinase N, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286242.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LEY5
      Conserved Domains (6) summary
      cd11622
      Location:37 → 100
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:149 → 215
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:246 → 320
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:840 → 1099
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:840 → 1165
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:436 → 517
      C2; C2 domain

    9. NM_001259291.2 → NP_001246220.1  protein kinase N, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246220.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K6U3
      Conserved Domains (6) summary
      cd11622
      Location:37 → 100
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:149 → 215
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:246 → 320
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:933 → 1192
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:933 → 1258
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:436 → 517
      C2; C2 domain

    10. NM_001299315.1 → NP_001286244.1  protein kinase N, isoform Q [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286244.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LF03
      Conserved Domains (6) summary
      cd11622
      Location:37 → 100
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:149 → 215
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:246 → 320
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:951 → 1210
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:951 → 1276
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:436 → 517
      C2; C2 domain

    11. NM_001299314.1 → NP_001286243.1  protein kinase N, isoform P [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286243.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LEI8
      Conserved Domains (6) summary
      cd11622
      Location:37 → 100
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:149 → 215
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:246 → 320
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:953 → 1212
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:953 → 1278
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:436 → 517
      C2; C2 domain

    12. NM_176111.2 → NP_788291.1  protein kinase N, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788291.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z7T1, Q960L7
      Related
      FBpp0087683
      Conserved Domains (6) summary
      cd11622
      Location:37 → 100
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:149 → 215
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:246 → 320
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:1080 → 1339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:1080 → 1405
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:436 → 517
      C2; C2 domain

    13. NM_001299312.1 → NP_001286241.1  protein kinase N, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286241.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LFX2
      Conserved Domains (6) summary
      cd11622
      Location:37 → 100
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:149 → 215
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:246 → 320
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:1150 → 1409
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:1150 → 1475
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:436 → 517
      C2; C2 domain

    14. NM_001259292.2 → NP_001246221.1  protein kinase N, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246221.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K727
      Conserved Domains (6) summary
      cd11622
      Location:52 → 115
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:164 → 230
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:261 → 335
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:948 → 1207
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:948 → 1273
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:451 → 532
      C2; C2 domain

    15. NM_001201966.2 → NP_001188895.1  protein kinase N, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188895.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K727
      Conserved Domains (6) summary
      cd11622
      Location:52 → 115
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:164 → 230
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:261 → 335
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:948 → 1207
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:948 → 1273
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:451 → 532
      C2; C2 domain

    16. NM_001201968.3 → NP_001188897.3  protein kinase N, isoform S [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JD07, A0A0B4JD60
      Conserved Domains (6) summary
      cd11622
      Location:131 → 194
      HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11623
      Location:243 → 309
      HR1_PKN_2; Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      cd11625
      Location:340 → 414
      HR1_PKN_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
      smart00220
      Location:1027 → 1286
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05589
      Location:1027 → 1352
      STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
      cl14603
      Location:530 → 611
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JD07 A0A0B4JD07
    A0A0B4K6U3 A0A0B4K6U3
    A0A0B4K727 A0A0B4K727
    A0A0B4LEI8 A0A0B4LEI8
    A0A0B4LEY5 A0A0B4LEY5
    A0A0B4LF03 A0A0B4LF03
    A0A0B4LFX2 A0A0B4LFX2
    A1Z7T0.1 A1Z7T0
    A1Z7T1 A1Z7T1
    A1Z7T2 A1Z7T2
    A1Z7T3 A1Z7T3
    A1Z7T4 A1Z7T4
    A8DY76 A8DY76
    E1JH15 E1JH15
    Q7YU74 Q7YU74
    Q960L7 Q960L7

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