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    panE 2-dehydropantoate 2-reductase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945065, updated on 3-Dec-2024

    Summary

    Official Symbol
    panE
    Official Full Name
    2-dehydropantoate 2-reductase
    Primary source
    ECOCYC:G6239
    Locus tag
    b0425
    See related
    ASAP:ABE-0001474
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    apbA; ECK0419
    Summary
    Sequence verified by mass spectrometry (obs=33870), Met is not clipped. [More information is available at EcoGene: EG13271]. 2-Dehydropantoate 2-reductase catalyzes the NADPH-dependent reduction of ketopantoate to pantoate. [More information is available at EcoCyc: G6239].
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    Genomic context

    Sequence:
    NC_000913.3 (443604..444515, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene geranyl diphosphate/farnesyl diphosphate synthase Neighboring gene exodeoxyribonuclease VII subunit XseB Neighboring gene tRNA uridine 4-sulfurtransferase Neighboring gene protein/nucleic acid deglycase 3 Neighboring gene nucleotide binding protein YajQ Neighboring gene putative transport protein YajR

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by EcoCyc

    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytoplasm  

    General protein information

    Preferred Names
    2-dehydropantoate 2-reductase
    NP_414959.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      443604..444515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414959.1 2-dehydropantoate 2-reductase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414959.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5Y960
      Conserved Domains (1) summary
      PRK06522
      Location:1 → 295
      PRK06522; 2-dehydropantoate 2-reductase; Reviewed
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