AP-1mu Adaptor Protein complex 1, mu subunit [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: AP-1muprovided by FlyBase
Official Full Name: Adaptor Protein complex 1, mu subunitprovided by FlyBase
Primary source: FLYBASE:FBgn0024833
Locus tag: Dmel_CG9388
See related: AllianceGenome:FB:FBgn0024833
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: AP-1 M; AP-1mu1; ap-1u; ap-47; AP-47; AP1mu; AP1mu1; AP47; apm1; APmu1; cg9388; CG9388; Dmel\CG9388; Dmu1; mu1
Summary: Enables clathrin adaptor activity. Involved in several processes, including compound eye development; negative regulation of endocytic recycling; and secretory granule organization. Located in clathrin-coated vesicle. Part of AP-1 adaptor complex. Is expressed in adult head and organism. Orthologous to human AP1M1 (adaptor related protein complex 1 subunit mu 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (9557712..9559525, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (5383434..5385247, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables clathrin adaptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables clathrin adaptor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables clathrin binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in compound eye development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in intracellular transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of endocytic recycling	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in secretory granule organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of AP-1 adaptor complex	IMP Inferred from Mutant Phenotype more info	PubMed
part_of AP-1 adaptor complex	IPI Inferred from Physical Interaction more info	PubMed
part_of AP-1 adaptor complex	ISS Inferred from Sequence or Structural Similarity more info
part_of clathrin adaptor complex	IEA Inferred from Electronic Annotation more info
is_active_in clathrin-coated vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in clathrin-coated vesicle	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain