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    EPHA2 EPH receptor A2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 692343, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EPHA2provided by VGNC
    Official Full Name
    EPH receptor A2provided by VGNC
    Primary source
    VGNC:VGNC:72235
    See related
    Ensembl:ENSMMUG00000018245
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EPHA2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (208621628..208652925)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (15053393..15084448, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene anoctamin-2 Neighboring gene Rho guanine nucleotide exchange factor 19 Neighboring gene vegetative cell wall protein gp1-like Neighboring gene family with sequence similarity 131 member C Neighboring gene chloride voltage-gated channel Kb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane-ephrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ephrin type-A receptor 2
    NP_001035768.1
    XP_028708593.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040678.1 → NP_001035768.1  ephrin type-A receptor 2 precursor

      See identical proteins and their annotated locations for NP_001035768.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ480434
      UniProtKB/TrEMBL
      G7MH44, Q1HKZ4
      Related
      ENSMMUP00000079185.1, ENSMMUT00000079767.1
      Conserved Domains (7) summary
      cd09543
      Location:902 → 971
      SAM_EPH-A2; SAM domain of EPH-A2 family of tyrosine kinase receptors
      smart00454
      Location:902 → 968
      SAM; Sterile alpha motif
      cd10480
      Location:28 → 201
      EphR_LBD_A2; Ligand Binding Domain of Ephrin type-A Receptor 2
      pfam00041
      Location:438 → 519
      fn3; Fibronectin type III domain
      pfam07714
      Location:613 → 871
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14575
      Location:556 → 608
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl21453
      Location:607 → 875
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      208621628..208652925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028852760.1 → XP_028708593.1  ephrin type-A receptor 2 isoform X1

      UniProtKB/TrEMBL
      F7E018, G7MH44
      Related
      ENSMMUP00000023985.3, ENSMMUT00000025638.4
      Conserved Domains (5) summary
      cd09543
      Location:848 → 917
      SAM_EPH-A2; SAM domain of EPH-A2 family of tyrosine kinase receptors
      pfam00041
      Location:384 → 462
      fn3; Fibronectin type III domain
      pfam14575
      Location:502 → 554
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl02704
      Location:1 → 147
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
      cl21453
      Location:553 → 821
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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