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    ilvA threonine deaminase [ Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ]

    Gene ID: 1255431, updated on 6-Oct-2023

    Summary

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    Gene symbol
    ilvA
    Gene description
    threonine deaminase
    Locus tag
    STM3905
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (strain: LT2, serovar: Typhimurium, sub-species: enterica, culture-collection: ATCC:700720, culture-collection: SGSC:1412, type-material: type strain of Salmonella enterica)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella
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    Genomic context

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    Sequence:
    NC_003197.2 (4113843..4115397)

    NC_003197.2Genomic Context describing neighboring genes Neighboring gene acetolactate synthase II, large subunit Neighboring gene acetolactate synthase II, small subunit Neighboring gene branched-chain amino-acid aminotransferase Neighboring gene dihydroxyacid dehydratase Neighboring gene putative cytoplasmic protein Neighboring gene putative cytoplasmic protein Neighboring gene positive LysR family regulator for ilvC Neighboring gene ketol-acid reductoisomerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003197.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analyses of variants of the Ser/Thr dehydratase IlvA provide insight into 2-aminoacrylate metabolism in Salmonella enterica. Borchert AJ, et al. J Biol Chem, 2018 Dec 14. PMID 30327426, Free PMC Article
    2. YjgF is required for isoleucine biosynthesis when Salmonella enterica is grown on pyruvate medium. Christopherson MR, et al. J Bacteriol, 2008 Apr. PMID 18296521, Free PMC Article
    3. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. McClelland M, et al. Nature, 2001 Oct 25. PMID 11677609

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. variants of the Ser/Thr dehydratase IlvA provide insight into 2-aminoacrylate metabolism in Salmonella enterica
      Title: Analyses of variants of the Ser/Thr dehydratase IlvA provide insight into 2-aminoacrylate metabolism in Salmonella enterica.
    2. Feedback inhibition of IlvA is required for the curative effect of isoleucine on glucose-serine medium of the YjgF mutant.
      Title: YjgF is required for isoleucine biosynthesis when Salmonella enterica is grown on pyruvate medium.
    Submit: New GeneRIF Correction

    General gene information

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    regulatory

    • Loc: 4113843-4113848 regulatory_class = ribosome_binding_site

    General protein information

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    Preferred Names
    threonine deaminase
    NP_462796.1
    • threonine dehydratase biosynthetic. (SW:THD1_SALTY)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003197.2 Reference assembly

      Range
      4113843..4115397
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_462796.1 threonine deaminase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

      See identical proteins and their annotated locations for NP_462796.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3S4FNG7, A0A403MKR9, A0A5H8JH11, A0A5U1NCD1, A0A5V0EEC9, A0A5Y5TG54, A0A5Y7WKM0, A0A5Y9YBE8, A0A742PAM8, A0A757EWD2, A0A8E9PX58, E8XIL6, V7IN19
      Conserved Domains (1) summary
      PRK09224
      Location:13 → 513
      PRK09224; threonine ammonia-lyase IlvA
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20506.3

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