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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012305.2 RefSeqGene
- Range
-
5010..208395
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1032
mRNA and Protein(s)
-
NM_001001549.3 → NP_001001549.1 growth factor receptor-bound protein 10 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (2), also known as hGrb10alpha, lacks an in-frame segment in the coding region, compared to variant 1. It encodes a shorter isoform (b), that is missing an internal segment compared to isoform a.
- Source sequence(s)
-
AC005153, AC080092
- Consensus CDS
-
CCDS47586.1
- UniProtKB/Swiss-Prot
-
Q13322
- Related
- ENSP00000349818.5, ENST00000357271.9
- Conserved Domains (4) summary
-
- cd01787
Location:166 → 248
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:441 → 548
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:283 → 362
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:380 → 421
- BPS; BPS (Between PH and SH2)
-
NM_001001550.3 → NP_001001550.1 growth factor receptor-bound protein 10 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (3), also known as hGrb10beta, differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (c) has a shorter N-terminus when compared to isoform a. Isoform c is encoded by transcript variants 4, 6, and 7.
- Source sequence(s)
-
AC005153, AC080092
- Consensus CDS
-
CCDS43583.1
- UniProtKB/Swiss-Prot
-
Q13322
- Related
- ENSP00000381790.2, ENST00000398810.6
- Conserved Domains (4) summary
-
- cd10415
Location:429 → 536
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:228 → 350
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- cd16141
Location:108 → 199
- RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
- pfam08947
Location:368 → 409
- BPS; BPS (Between PH and SH2)
-
NM_001001555.3 → NP_001001555.1 growth factor receptor-bound protein 10 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (c) has a shorter N-terminus when compared to isoform a. Isoform c is encoded by transcript variants 3, 4, 6, and 7.
- Source sequence(s)
-
AC004920, AC005153, AC080092
- Consensus CDS
-
CCDS43583.1
- UniProtKB/Swiss-Prot
-
Q13322
- Related
- ENSP00000338543.3, ENST00000335866.7
- Conserved Domains (4) summary
-
- cd10415
Location:429 → 536
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:228 → 350
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- cd16141
Location:108 → 199
- RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
- pfam08947
Location:368 → 409
- BPS; BPS (Between PH and SH2)
-
NM_001350814.2 → NP_001337743.1 growth factor receptor-bound protein 10 isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform a.
- Source sequence(s)
-
AC004920, AC005153, AC080092
- Consensus CDS
-
CCDS43582.1
- UniProtKB/Swiss-Prot
- A4D258, A7VJ95, A8K0E6, D3DVM9, O00427, O00701, O75222, Q13322, Q92606, Q92907, Q92948
- Related
- ENSP00000385770.1, ENST00000401949.6
- Conserved Domains (4) summary
-
- cd01787
Location:166 → 248
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:487 → 594
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:286 → 408
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:426 → 467
- BPS; BPS (Between PH and SH2)
-
NM_001350815.2 → NP_001337744.1 growth factor receptor-bound protein 10 isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) encodes isoform d.
- Source sequence(s)
-
AC004920, AC005153, AC080092
- Consensus CDS
-
CCDS87504.1
- UniProtKB/TrEMBL
-
A0A2R8YCL1
- Related
- ENSP00000493728.1, ENST00000644879.1
- Conserved Domains (4) summary
-
- cd01787
Location:204 → 286
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:525 → 632
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:324 → 446
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:464 → 505
- BPS; BPS (Between PH and SH2)
-
NM_001350816.3 → NP_001337745.2 growth factor receptor-bound protein 10 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (6), as well as variants 3, 4, and 7, encodes isoform c.
- Source sequence(s)
-
AC004920, AC005153, AC080092
- Consensus CDS
-
CCDS43583.1
- Conserved Domains (4) summary
-
- cd10415
Location:429 → 536
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:228 → 350
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- cd16141
Location:108 → 199
- RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
- pfam08947
Location:368 → 409
- BPS; BPS (Between PH and SH2)
-
NM_001371008.1 → NP_001357937.1 growth factor receptor-bound protein 10 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (7), as well as variants 3, 4, and 6, encodes isoform c.
- Source sequence(s)
-
AC004920, AC005153, AC080092
- Consensus CDS
-
CCDS43583.1
- Related
- ENSP00000495341.2, ENST00000645075.2
- Conserved Domains (4) summary
-
- cd10415
Location:429 → 536
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:228 → 350
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- cd16141
Location:108 → 199
- RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
- pfam08947
Location:368 → 409
- BPS; BPS (Between PH and SH2)
-
NM_001371009.1 → NP_001357938.1 growth factor receptor-bound protein 10 isoform f
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) encodes the longest isoform (f).
- Source sequence(s)
-
AC004920, AC005153, AC080092
- Conserved Domains (3) summary
-
- cd10415
Location:536 → 643
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:335 → 457
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- cd16141
Location:215 → 306
- RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
50590068..50793453 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017012061.3 → XP_016867550.1 growth factor receptor-bound protein 10 isoform X11
- Conserved Domains (4) summary
-
- cd01787
Location:154 → 235
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:474 → 581
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:273 → 395
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:413 → 454
- BPS; BPS (Between PH and SH2)
-
XM_047420243.1 → XP_047276199.1 growth factor receptor-bound protein 10 isoform X10
-
XM_047420233.1 → XP_047276189.1 growth factor receptor-bound protein 10 isoform X6
-
XM_047420241.1 → XP_047276197.1 growth factor receptor-bound protein 10 isoform X8
- UniProtKB/Swiss-Prot
- A4D258, A7VJ95, A8K0E6, D3DVM9, O00427, O00701, O75222, Q13322, Q92606, Q92907, Q92948
- Related
- ENSP00000381793.2, ENST00000398812.6
-
XM_017012034.2 → XP_016867523.1 growth factor receptor-bound protein 10 isoform X5
-
XM_047420252.1 → XP_047276208.1 growth factor receptor-bound protein 10 isoform X7
-
XM_047420244.1 → XP_047276200.1 growth factor receptor-bound protein 10 isoform X10
-
XM_047420240.1 → XP_047276196.1 growth factor receptor-bound protein 10 isoform X6
-
XM_024446726.2 → XP_024302494.1 growth factor receptor-bound protein 10 isoform X3
- Conserved Domains (4) summary
-
- cd01787
Location:250 → 331
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:570 → 677
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:369 → 491
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:509 → 550
- BPS; BPS (Between PH and SH2)
-
XM_017012030.3 → XP_016867519.1 growth factor receptor-bound protein 10 isoform X2
-
XM_017012031.3 → XP_016867520.1 growth factor receptor-bound protein 10 isoform X4
-
XM_017012029.3 → XP_016867518.1 growth factor receptor-bound protein 10 isoform X1
-
XM_047420253.1 → XP_047276209.1 growth factor receptor-bound protein 10 isoform X7
-
XM_047420254.1 → XP_047276210.1 growth factor receptor-bound protein 10 isoform X7
-
XM_047420255.1 → XP_047276211.1 growth factor receptor-bound protein 10 isoform X7
-
XM_047420238.1 → XP_047276194.1 growth factor receptor-bound protein 10 isoform X6
-
XM_047420232.1 → XP_047276188.1 growth factor receptor-bound protein 10 isoform X5
-
XM_047420250.1 → XP_047276206.1 growth factor receptor-bound protein 10 isoform X11
-
XM_024446729.2 → XP_024302497.1 growth factor receptor-bound protein 10 isoform X11
- Conserved Domains (4) summary
-
- cd01787
Location:154 → 235
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:474 → 581
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:273 → 395
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:413 → 454
- BPS; BPS (Between PH and SH2)
-
XM_047420249.1 → XP_047276205.1 growth factor receptor-bound protein 10 isoform X11
-
XM_047420247.1 → XP_047276203.1 growth factor receptor-bound protein 10 isoform X11
-
XM_047420236.1 → XP_047276192.1 growth factor receptor-bound protein 10 isoform X6
-
XM_047420248.1 → XP_047276204.1 growth factor receptor-bound protein 10 isoform X11
-
XM_047420246.1 → XP_047276202.1 growth factor receptor-bound protein 10 isoform X11
-
XM_047420235.1 → XP_047276191.1 growth factor receptor-bound protein 10 isoform X6
-
XM_047420234.1 → XP_047276190.1 growth factor receptor-bound protein 10 isoform X6
-
XM_047420245.1 → XP_047276201.1 growth factor receptor-bound protein 10 isoform X11
-
XM_047420251.1 → XP_047276207.1 growth factor receptor-bound protein 10 isoform X11
-
XM_047420237.1 → XP_047276193.1 growth factor receptor-bound protein 10 isoform X6
-
XM_017012058.1 → XP_016867547.1 growth factor receptor-bound protein 10 isoform X11
- Conserved Domains (4) summary
-
- cd01787
Location:154 → 235
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:474 → 581
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:273 → 395
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:413 → 454
- BPS; BPS (Between PH and SH2)
-
XM_017012062.3 → XP_016867551.1 growth factor receptor-bound protein 10 isoform X11
- Conserved Domains (4) summary
-
- cd01787
Location:154 → 235
- GRB7_RA; RA (RAS-associated like) domain of Grb7
- cd10415
Location:474 → 581
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:273 → 395
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- pfam08947
Location:413 → 454
- BPS; BPS (Between PH and SH2)
-
XM_017012045.1 → XP_016867534.1 growth factor receptor-bound protein 10 isoform X7
- UniProtKB/Swiss-Prot
-
Q13322
- Related
- ENSP00000385189.1, ENST00000402578.5
- Conserved Domains (4) summary
-
- cd10415
Location:429 → 536
- SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
- cd01259
Location:228 → 350
- PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
- cd16141
Location:108 → 199
- RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
- pfam08947
Location:368 → 409
- BPS; BPS (Between PH and SH2)
-
XM_047420242.1 → XP_047276198.1 growth factor receptor-bound protein 10 isoform X9
-
XM_047420256.1 → XP_047276212.1 growth factor receptor-bound protein 10 isoform X12
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
50751214..50954643 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054357968.1 → XP_054213943.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357966.1 → XP_054213941.1 growth factor receptor-bound protein 10 isoform X10
-
XM_054357957.1 → XP_054213932.1 growth factor receptor-bound protein 10 isoform X6
-
XM_054357964.1 → XP_054213939.1 growth factor receptor-bound protein 10 isoform X8
- UniProtKB/Swiss-Prot
- A4D258, A7VJ95, A8K0E6, D3DVM9, O00427, O00701, O75222, Q13322, Q92606, Q92907, Q92948
-
XM_054357956.1 → XP_054213931.1 growth factor receptor-bound protein 10 isoform X5
-
XM_054357979.1 → XP_054213954.1 growth factor receptor-bound protein 10 isoform X7
-
XM_054357953.1 → XP_054213928.1 growth factor receptor-bound protein 10 isoform X3
-
XM_054357967.1 → XP_054213942.1 growth factor receptor-bound protein 10 isoform X10
-
XM_054357952.1 → XP_054213927.1 growth factor receptor-bound protein 10 isoform X2
-
XM_054357954.1 → XP_054213929.1 growth factor receptor-bound protein 10 isoform X4
-
XM_054357951.1 → XP_054213926.1 growth factor receptor-bound protein 10 isoform X1
-
XM_054357980.1 → XP_054213955.1 growth factor receptor-bound protein 10 isoform X7
-
XM_054357981.1 → XP_054213956.1 growth factor receptor-bound protein 10 isoform X7
-
XM_054357962.1 → XP_054213937.1 growth factor receptor-bound protein 10 isoform X6
-
XM_054357955.1 → XP_054213930.1 growth factor receptor-bound protein 10 isoform X5
-
XM_054357976.1 → XP_054213951.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357973.1 → XP_054213948.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357975.1 → XP_054213950.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357971.1 → XP_054213946.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357960.1 → XP_054213935.1 growth factor receptor-bound protein 10 isoform X6
-
XM_054357974.1 → XP_054213949.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357970.1 → XP_054213945.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357959.1 → XP_054213934.1 growth factor receptor-bound protein 10 isoform X6
-
XM_054357958.1 → XP_054213933.1 growth factor receptor-bound protein 10 isoform X6
-
XM_054357969.1 → XP_054213944.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357977.1 → XP_054213952.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357961.1 → XP_054213936.1 growth factor receptor-bound protein 10 isoform X6
-
XM_054357972.1 → XP_054213947.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357978.1 → XP_054213953.1 growth factor receptor-bound protein 10 isoform X11
-
XM_054357963.1 → XP_054213938.1 growth factor receptor-bound protein 10 isoform X7
-
XM_054357965.1 → XP_054213940.1 growth factor receptor-bound protein 10 isoform X9
-
XM_054357982.1 → XP_054213957.1 growth factor receptor-bound protein 10 isoform X12
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_005311.4: Suppressed sequence
- Description
- NM_005311.4: This RefSeq was removed because currently there is insufficient support for the transcript.