RpL40 Ribosomal protein L40 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: RpL40provided by FlyBase
Official Full Name: Ribosomal protein L40provided by FlyBase
Primary source: FLYBASE:FBgn0003941
Locus tag: Dmel_CG2960
See related: AllianceGenome:FB:FBgn0003941
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:RE10554; CEP52; CG2960; Dmel\CG2960; Dub52; DUb52; L40; L40e; Rpl40; RPL40; Ub52; Ubi-f; Ubi-f52; Ubiq
Summary: Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Part of cytosolic large ribosomal subunit. Is expressed in several structures, including adult heart; embryonic/larval fat body; embryonic/larval hindgut; embryonic/larval salivary gland; and germinal proliferation center. Orthologous to human UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (4227699..4228561)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (4227699..4228561)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein tag activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein tag activity	ISS Inferred from Sequence or Structural Similarity more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	TAS Traceable Author Statement more info	PubMed
enables ubiquitin protein ligase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cytoplasmic translation	TAS Traceable Author Statement more info	PubMed
involved_in modification-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein modification process	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	ISS Inferred from Sequence or Structural Similarity more info
involved_in translation	IEA Inferred from Electronic Annotation more info
involved_in translation	TAS Traceable Author Statement more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of cytosolic large ribosomal subunit	IDA Inferred from Direct Assay more info	PubMed
part_of cytosolic large ribosomal subunit	TAS Traceable Author Statement more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

Names: CG2960-PA; CG2960-PB; RpL40-PA; RpL40-PB; ubiquitin; ubiquitin 52-AA extension protein; ubiquitin fusion 52

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